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논문 기본 정보

자료유형
학술저널
저자정보
Ye-Jin Lee (Korea Institute of Oriental Medicine (KIOM)) Ik Soo Lee (Korea Institute of Oriental Medicine (KIOM)) Young Sook Kim (Korea Institute of Oriental Medicine (KIOM)) Sang-Woo Ahn (Korea Institute of Oriental Medicine (KIOM))
저널정보
한국생약학회 Natural Product Sciences Natural Product Sciences Vol.30 No.2
발행연도
2024.6
수록면
143 - 147 (5page)
DOI
10.20307/nps.2024.30.2.143

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초록· 키워드

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Many attempts are being made to find safe and therapeutic materials from natural sources. Laminariae Thallus is said to treat swelling of the face in the Dongui-Bogam and has been used in Traditional Korean Medicine to treat boils and chronic gallstones. Recently Laminariae Thallus has been utilized as a cosmetic material for its moisturizing and whitening properties. In this study, water and ethanolic extracts (30%, 50% and 80%) of Laminariae Thallus were prepared. Their regeneration effects were evaluated by cell proliferation and migration in human keratinocytes (HaCaT cells) and tail fin regeneration assay in zebrafish larvae. An 80% ethanol extract (100 μg/mL) of Laminariae Thallus was found to have the strongest ability on the migration of cells. In the tail fin regeneration experiment using zebrafish larvae, 80% ethanol extract (100 and 50 μg/mL) showed a high regeneration effect compared to the control. In conclusion, this study provides a scientific basis for the use of Laminariae Thallus extract for skin regeneration and suggests that it has great potential as a regenerative material for future natural cosmetics.

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Abstract
Introduction
Experimental
Results and Discussion
References

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