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논문 기본 정보

자료유형
학술저널
저자정보
Jung-Ho Yun (Department of Neurological Surgery, College of Medicine, Dankook University)
저널정보
대한신경손상학회 Korean Journal of Neurotrauma Korean Journal of Neurotrauma 제20권 제1호
발행연도
2024.3
수록면
5 - 7 (3page)
DOI
https://doi.org/10.13004/kjnt.2024.20.e14

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초록· 키워드

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Perioperative or Intraoperative surveillance of blood flow in the brain and identification of disturbances are among the most critical challenges of modern neurocritical care field. The method for monitoring cerebral blood flow (CBF) is generally indirectly calculated through intracerebral pressure and cerebral perfusion pressure, which is currently widely used in South Korea. However, an accurate quantitative system requires the use of an invasive method, which includes a method using a thermal diffusion probe that measures CBF and a method that measures and calculates tissue oxygen saturation through brain oxygenation. These methods have the disadvantage that it is invasive, the measured values change depending on the installation of the probe, and the accuracy in interpreting these measured values is not relatively guaranteed. Accordingly, optical contrast measurement is a method of monitoring CBF that can compensate for this weakness which is not actively used yet but is mainly studied in laboratories. For the past year, this author has studied surveillance of brain hemodynamics using the above-mentioned optical imaging approach at the University of California, Irvine: Beckman Laser Institute in Irvine, California. Therefore, I would like to briefly introduce these widefield optical imaging approaches which are consisted of three main types of measurement for cerebral hemodynamics including the following optical intrinsic signal imaging, laser speckle imaging (LSI) and spatial frequency domain imaging (SFDI). These optical approaches are a representative multimodal imaging that uses technique called optical absorption, optical scattering, and speckle contrast to detect CBF alteration. Since these change of light contrast fundamentals depending on specific wavelength, it is recommended to match the optimized light wavelength for the characteristics of the equipment.3) Among these ways, optical imaging properties studied related to traumatic brain injury (TBI) are LSI and SFDI.

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