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논문 기본 정보

자료유형
학술저널
저자정보
Lee Jee-In (Division of Rheumatology, Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea) Park Jun Won (Division of Rheumatology, Department of Internal Medicine, Seoul National University Hospital, Department of Internal Medicine, Seoul, Korea) Jung Youjin (Division of Rheumatology, Department of Internal Medicine, Seoul National University Hospital, Department of Internal Medicine, Seoul, Korea) Shin Kichul (Division of Rheumatology, Department of Internal Medicine, Seoul Metropolitan Government-Seoul National University Boramae Medical Center, Seoul, Korea.Department of Internal Medicine, Seoul) Se Rim Choi (Division of Rheumatology, Department of Internal Medicine, 1Seoul National University Bundang Hospital, Seongnam, Korea) Kang Eun Ha (Division of Rheumatology, Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, KoreaDivision of Rheumatology, Department of Internal Medicine, Seoul Univers) Lee Yun Jong (Division of Rheumatology, Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, KoreaDivision of Rheumatology, Department of Internal Medicine, Seoul Univers) Yoo Jong Jin (Division of Rheumatology, Department of Internal Medicine, Kangdong Sacred Heart Hospital, Seoul, Korea) Ha You-Jung (Division of Rheumatology, Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, KoreaDivision of Rheumatology, Department of Internal Medicine, Seoul Univers)
저널정보
대한류마티스학회 대한류마티스학회지 Journal of Rheumatic Diseases Vol.31 No.3
발행연도
2024.7
수록면
160 - 170 (11page)
DOI
10.4078/jrd.2024.0007

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Objective: Giant cell arteritis (GCA) is a large-vessel vasculitis that primarily affects elderly individuals. However, data regarding Korean patients with GCA are scarce owing to its extremely low prevalence in East Asia. This study aimed to investigate the clinical characteristics of Korean patients with GCA and their outcomes, focusing on relapse. Methods: The medical records of 27 patients with GCA treated at three tertiary hospitals between 2007 and 2022 were retrospectively reviewed. Results: Seventeen (63.0%) patients were females, and the median age at diagnosis was 75 years. Large vessel involvement (LVI) was detected in 12 (44.4%) patients, and polymyalgia rheumatica (PMR) was present in 14 (51.9%) patients. Twelve (44.4%) patients had fever at onset. The presence of LVI or concurrent PMR at diagnosis was associated with a longer time to normalization of the C-reactive protein level (p=0.039) or erythrocyte sedimentation rate (p=0.034). During follow-up (median: 33.8 months), four (14.8%) patients experienced relapse. Kaplan-Meier analyses showed that relapse was associated with visual loss (p=0.008) and the absence of fever (p=0.004) at onset, but not with LVI or concurrent PMR. Conclusion: Concurrent PMR and LVI were observed in approximately half of Korean patients with GCA, and the elapsed time to normalization of inflammatory markers in these patients was longer. The relapse rate in Korean GCA is lower than that in Western countries, and afebrile patients or patients with vision loss at onset have a higher risk of relapse, suggesting that physicians should carefully monitor patients with these characteristics.

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