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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2008.12
- 수록면
- 685 - 688 (4page)
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초록· 키워드
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The ubiquitin-proteasome system is associated with homeostasis and several biological processes. The level of ubiquitin-proteasome system is regulated by deubiquitinating enzymes. Deubiquitinating enzymes are subdivided into ubiquitin C-terminal hydrolases (UCH) and ubiquitin-specific proteases. Previous studies show that UCH isozymes have critical function during neurogenesis and spermatogenesis, whereas UCH function has been limited in kidney. We demonstrated different levels and expressions of the UCH-L1 and UCH-L3, such as the predominant expression of UCH-L1 in renal papilla whereas UCHL3 expression was high in the renal medulla and cortex. These results suggest that different distributions of two UCH isozymes may indicate the distinct functions in mouse nephrology.
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등록된 정보가 없습니다.
참고문헌 (16)
참고문헌 신청
1. [학술지(정기간행물)] - Capasso, G. / 1987 / Renal bicarbonate reabsorption in the rat. II. Distal tubule load dependence and effect of hypokalemia / J. Clin. Invest 80 (2) : 409 ~ 414
2. [학술지(정기간행물)] - Chang, H. / 2001 / A numerical model of acid-base transport in rat distal tubule / Am. J. Physiol. Renal. Physiol 281 (2) : F222 ~ F243
3. [학술지(정기간행물)] - Debonneville, C. / 2004 / Participation of the ubiquitin-conjugating enzyme UBE2E3 in Nedd4-2-dependent regulation of the epithelial Na+ channel / Mol. Cell. Biol 24 (6) : 2397 ~ 2409
4. [학술지(정기간행물)] - Diomedi-Camassei, F. / 2005 / Protein gene product 9.5 and ubiquitin are expressed in metabolically active epithelial cells of normal and pathologic human kidney / Nephrol. Dial. Transplant 20 (12) : 2714 ~ 2719
5. [학술지(정기간행물)] - Kwon, J. / 2006 / The region-specific functions of two ubiquitin C-terminal hydrolase isozymes along the epididymis / Exp. Anim 55 (1) : 35 ~ 43
2. [학술지(정기간행물)] - Chang, H. / 2001 / A numerical model of acid-base transport in rat distal tubule / Am. J. Physiol. Renal. Physiol 281 (2) : F222 ~ F243
3. [학술지(정기간행물)] - Debonneville, C. / 2004 / Participation of the ubiquitin-conjugating enzyme UBE2E3 in Nedd4-2-dependent regulation of the epithelial Na+ channel / Mol. Cell. Biol 24 (6) : 2397 ~ 2409
4. [학술지(정기간행물)] - Diomedi-Camassei, F. / 2005 / Protein gene product 9.5 and ubiquitin are expressed in metabolically active epithelial cells of normal and pathologic human kidney / Nephrol. Dial. Transplant 20 (12) : 2714 ~ 2719
5. [학술지(정기간행물)] - Kwon, J. / 2006 / The region-specific functions of two ubiquitin C-terminal hydrolase isozymes along the epididymis / Exp. Anim 55 (1) : 35 ~ 43
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UCI(KEPA) : I410-ECN-0101-2009-510-015707217