지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2007.11
- 수록면
- 406 - 411 (6page)
이용수
초록· 키워드
오류제보하기
Purpose: Studying the prognostic factors of distant metastasis is quite important for predicting these patients’ prognosis and also for providing standards for post-operative adjuvant chemotherapy. Microbiological studies currently enable researchers to look for new predictors of distant metastasis in patients with colon cancers. In this study, the VEGF-C expression and stain rate of D2-40 were investigated as prognostic factors.
Methods: 79 Specimens were collected from the patients who underwent colorectal operation and they were pathologicaly diagnosed with cancer at Chung-Ang University hospital from March, 2003 to Sept. 2005. The specimens were immunohistochemically stained to detect the VEGF-c expression and the D2- 40 stain rate.
Results: The VEGF-C expression was related to lymph node metastasis, tumor embolism and the frequency of the Tstage, but it was not related to progression of cancer. The D2-40 stained lymphatic density was significantly increased in the cases with lymph node metastasis and in the tumor embolism cases; furthermore, the density became higher in relation to the increased T-stage and progression of cancer.
Conclusion: The VEGF-C expression and lymphatic vessel density appear to be prognostic factors for colon cancer.
Methods: 79 Specimens were collected from the patients who underwent colorectal operation and they were pathologicaly diagnosed with cancer at Chung-Ang University hospital from March, 2003 to Sept. 2005. The specimens were immunohistochemically stained to detect the VEGF-c expression and the D2- 40 stain rate.
Results: The VEGF-C expression was related to lymph node metastasis, tumor embolism and the frequency of the Tstage, but it was not related to progression of cancer. The D2-40 stained lymphatic density was significantly increased in the cases with lymph node metastasis and in the tumor embolism cases; furthermore, the density became higher in relation to the increased T-stage and progression of cancer.
Conclusion: The VEGF-C expression and lymphatic vessel density appear to be prognostic factors for colon cancer.
목차
서론
방법
결과
고찰
결론
REFERENCES
참고문헌 (17)
참고문헌 신청
1. [기타자료] - Ministry of health and welfare / 2003 / Korean cancer research 2003
2. [학술지(정기간행물)] - Masood R / 2001 / Vascular endothelial growth factor (VEGF) is an autocrine growth factor for VEGF receptor-positive human tumors / Blood 98 : 1904 ~ 1913
3. [학술지(정기간행물)] - Leung DW / 1989 / Vascular endothelial growth factor is a secreted angiogenic mitogen / Science 246 : 1306 ~ 1309
4. [학술지(정기간행물)] - Kahn HJ / 2002 / Monoclonal antibody D2-40, a new marker of lymphatic endothelium, reacts with Kaposi's sarcoma and a subset of angiosarcoma / Mol Pathol 15 : 434 ~ 440
5. [학술지(정기간행물)] - Connolly DT / 1989 / Tumor vascular permeability factor stimulates endothelial cell growth and angiogenesis / J Clin Inves 84 : 1470 ~ 1478
2. [학술지(정기간행물)] - Masood R / 2001 / Vascular endothelial growth factor (VEGF) is an autocrine growth factor for VEGF receptor-positive human tumors / Blood 98 : 1904 ~ 1913
3. [학술지(정기간행물)] - Leung DW / 1989 / Vascular endothelial growth factor is a secreted angiogenic mitogen / Science 246 : 1306 ~ 1309
4. [학술지(정기간행물)] - Kahn HJ / 2002 / Monoclonal antibody D2-40, a new marker of lymphatic endothelium, reacts with Kaposi's sarcoma and a subset of angiosarcoma / Mol Pathol 15 : 434 ~ 440
5. [학술지(정기간행물)] - Connolly DT / 1989 / Tumor vascular permeability factor stimulates endothelial cell growth and angiogenesis / J Clin Inves 84 : 1470 ~ 1478
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UCI(KEPA) : I410-ECN-0101-2013-514-002683047