지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
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초록· 키워드
오류제보하기
Cervical cancer is the third most common cancer in women worldwide and there is a significant association between human papillomavirus (HPV) infection and cervical cancer. Certain HPV groups, labeled high-risk (HR) HPV groups, are strongly associated with malignancies of the human cervix. HPV prevalence and genotype distribution were analyzed using the REBA HPV-ID<SUP>®</SUP> (YD Diagnostics, Yongin, Korea) assay based on the reverse blot hybridization assay (REBA) with a total of 324 liquid-based cytology samples from women in Western Shandong Province, East China and results were compared with cytological diagnosis. Most of the HPV genotypes that were detected in high-grade cervical lesions were HR-HPV genotypes such as HPV 16, 18, 33, 53, and 58. The prevalence of these HR-HPV genotypes increased in high-grade cervical lesions. However, from low- to high-grade cervical lesions, the ability to detect LR-HPV genotypes decreased. Additionally, in general, the single HPV genotype infection rate increases in proportion to the severity of the lesion. The study findings suggest that a currently available preventive vaccine against HPV 16 and 18 may have limited effectiveness for prevention of all HPV infection in this province. Finally, based on these findings, these data could guide national or regional vaccination programs in the Western Shandong Province of East China to substantially reduce the burden of cervical lesions.
목차
INTRODUCTION
MATERIALS AND METHODS
RESULTS
DISCUSSION
REFERENCES
참고문헌 (15)
참고문헌 신청
[학술지(정기간행물)] - Agarossi A / 2009 / Prevalence and type distribution of high-risk human papillomavirus infection in women undergoing voluntary cervical cancer screening in Italy / J Med Virol 81 : 529 ~ 535
[학술지(정기간행물)] - Bao YP / 2008 / Human papillomavirus type distribution in women from Asia: a meta-analysis / Int J Gynecol Cancer 18 : 71 ~ 79
[학술지(정기간행물)] - Bosch FX / 2008 / Epidemiology and natural history of human papillomavirus infections and type-specific implications in cervical neoplasia / Vaccine 10 : K1 ~ 16
[학술지(정기간행물)] - Bosch FX / 2003 / Chapter 1: human papillomavirus and cervical cancer - burden and assessment of causality / J Natl Cancer Inst Monogr 31 : 3 ~ 13
[학술지(정기간행물)] - Bouvard V / 2009 / A review of human carcinogens-part B: biological agents / Lancet Oncol 10 : 321 ~ 322
[학술지(정기간행물)] - Bao YP / 2008 / Human papillomavirus type distribution in women from Asia: a meta-analysis / Int J Gynecol Cancer 18 : 71 ~ 79
[학술지(정기간행물)] - Bosch FX / 2008 / Epidemiology and natural history of human papillomavirus infections and type-specific implications in cervical neoplasia / Vaccine 10 : K1 ~ 16
[학술지(정기간행물)] - Bosch FX / 2003 / Chapter 1: human papillomavirus and cervical cancer - burden and assessment of causality / J Natl Cancer Inst Monogr 31 : 3 ~ 13
[학술지(정기간행물)] - Bouvard V / 2009 / A review of human carcinogens-part B: biological agents / Lancet Oncol 10 : 321 ~ 322
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Human Papillomavirus Genotype Distribution Among 18,815 Women in 13 Korean Cities and Relationship With Cervical Cytology Findings
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High-risk Human Papillomavirus Genotypes in Cervical Lesions and Vaccination Challenges in China
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Prevalence of human papillomavirus genotypes and precancerous cervical lesions in a screening population in the Republic of Korea, 2014–2016
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A Review of HPV Prevalence Research
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Clinical significance of human papillomavirus genotyping
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Human Papillomavirus Genotyping and p16INK4a Expression in Cervical Lesions: A Combined Test to Avoid Cervical Cancer Progression
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Performance of HPV E6/E7 mRNA Genotyping Test on Paired Cervical Cancer Exfoliated Cells and Formalin Fixed Paraffin Embedded Tissues
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The Impact of High-Risk HPV Genotypes Other Than HPV 16/18 on the Natural Course of Abnormal Cervical Cytology: A Korean HPV Cohort Study
Cancer Research and Treatment
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Distribution of Oncogenic Human Papillomavirus Genotypes at High Grade Cervical Lesions above CIN 2 Grade with Histological Diagnosis
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Sequencing analysis of HPV-other type on an HPV DNA chip
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Combined SYBR Green real-time polymerase chain reaction and microarray method for the simultaneous determination of human papillomavirus loads and genotypes
Obstetrics & Gynecology Science
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Detection of High-Risk Human Papillomaviruses in the Prevention of Cervical Cancer in India
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Current Status of Human Papillomavirus Infection and Introduction of Vaccination to the National Immunization Program in Korea: an Overview
Journal of Korean Medical Science
2018 .01
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UCI(KEPA) : I410-ECN-0101-2016-510-001658713