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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.6
- 수록면
- 199 - 206 (8page)
- DOI
- 10.14815/kjdm.2016.43.2.199
이용수
초록· 키워드
오류제보하기
In this study, the characteristics of the bovine serum albumin (BSA)-containing bone-like apatite (BLAp) coated on titanium by immersion in simulated body fluid (SBF) were investigated. Titanium disks used as substrates were treated using anodic oxidation and hydrothermal treatments. A mSBF (modified-SBF) which contains twice of the concentration of Ca and P ions compared with that of standard SBF was used for coating BLAp layer. BSAs were premixed with a CaCl2 and a KH2PO4 solutions, respectively, in order to prepare Ca-mSBF and P-mSBF. The S-BLAp, Ca-BLAp, and P-BLAp groups were fabricated by soaking titanium specimens in mSBF, Ca-mSBF, and P-mSBF, respectively. The morphology of the crystallites observed in the Ca-BLAp and P-BLAp groups was more rounded compared with that of the S-BLAp group. In the cross-sectional images of BLAp layers, the S-BLAp and Ca-BLAp groups showed the well-aligned crystallites, while the P-BLAp group showed the randomly aligned crystallites. The Hydroxyapatite (HAp) crystalline structure was dominant for all groups. The XRD patterns of the Ca-BLAp group showed that HAp crystals were aligned along the c-axis. The crystallinity of P-BLAp group was lower than that of the Ca-BLAp group. The amide peaks related to BSA were identified on FT-IR spectra for the BSA-containing BLAp groups. The amount of dissolution of Ca and P ions was high in the S-BLAp group, while that was low in the Ca-BLAp group. After the dissolution experiment, amide peaks were still observed in the Ca-BLAp and P-BLAp groups, which inferred that BSAs were released slowly in BSA-containing BLAp groups.
목차
〈Abstract〉
Ⅰ. INTRODUCTION
Ⅱ. MATERIALS AND METHODS
Ⅲ. RESULTS AND DISCUSSION
Ⅳ. CONCLUSION
Ⅵ. REFERENCES
참고문헌 (21)
참고문헌 신청
[학술지(정기간행물)] - Agrawal CM / 1995 / Protein release kinetics of a biodegradable implant for fracture non-unions / Biomaterials 16 : 1255 ~ 1260
[학술지(정기간행물)] - Baig AA / 1999 / Relationships Among Carbonated Apatite Solubility, Crystallite Size, and Microstrain Parameters / Calcif Tissue Int 64 : 437 ~ 449
[학술지(정기간행물)] - Bayraktar D / 1999 / Chemical Preparation of Carbonated Calcium Hydroxyapatite Powders at 37℃in Urea-containing Synthetic Body Fluids / J Eur Ceramic Society 19 : 2573 ~ 2579
[학술지(정기간행물)] - Combes C / 2002 / Adsorption of proteins and calcium phosphate materials bioactivity / Biomaterials 23 : 2817 ~ 2823
[학술지(정기간행물)] - Dorozhkin SV / 2003 / The influence of bovine serum albumin on the crystallization of calcium phosphates from a revised simulated body fluid / Colloids and Surfaces A : Physicochem Eng Aspects 215 : 191 ~ 199
[학술지(정기간행물)] - Baig AA / 1999 / Relationships Among Carbonated Apatite Solubility, Crystallite Size, and Microstrain Parameters / Calcif Tissue Int 64 : 437 ~ 449
[학술지(정기간행물)] - Bayraktar D / 1999 / Chemical Preparation of Carbonated Calcium Hydroxyapatite Powders at 37℃in Urea-containing Synthetic Body Fluids / J Eur Ceramic Society 19 : 2573 ~ 2579
[학술지(정기간행물)] - Combes C / 2002 / Adsorption of proteins and calcium phosphate materials bioactivity / Biomaterials 23 : 2817 ~ 2823
[학술지(정기간행물)] - Dorozhkin SV / 2003 / The influence of bovine serum albumin on the crystallization of calcium phosphates from a revised simulated body fluid / Colloids and Surfaces A : Physicochem Eng Aspects 215 : 191 ~ 199
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UCI(KEPA) : I410-ECN-0101-2017-515-000875179