지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한외과학회 Annals of Surgical Treatment and Research Annals of Surgical Treatment and Research Vol.91 No.1
- 발행연도
- 2016.6
- 수록면
- 29 - 36 (8page)
이용수
초록· 키워드
오류제보하기
Purpose: Radical antegrade modular pancreatosplenectomy (RAMPS) is expected to be favorable for obtaining the negative tangential margin with oncologic feasibility through the horizontal dissection in a right-to-left fashion for radical lymph node dissections.
Methods: From January 2007 to February 2015, a total of 30 RAMPS and 19 conventional distal pancreatectomy (DP) cases were enrolled. The demographics, perioperative and survival outcomes were compared according to the type of surgery.
Results: The mean operative time, blood loss and length of hospital stay were similar between 2 groups. Morbidities were reported in 14 cases of RAMPS (46.7%) and 8 cases of DP (42.1%) (P = 0.777). The rate of negative tangential margin (96.2%) and the number of harvested lymph nodes (mean ± standard deviation, 21.5 ± 8.3) were significantly higher in RAMPS group (P = 0.011, P = 0.003, respectively). In terms of survival outcomes, there was no significant difference in regard to the overall 3-year disease-free survival (DFS; 30.4% in RAMPS vs. 35.0% in DP, P = 0.354) or overall survival (OS; 29.9% vs. 29.4%, P = 0.429) between the 2 groups. After exclusion of cases with nodal invasion, however, the RAMPS group had a longer DFS than the DP group (55.6% vs. 27.3%, P = 0.048) although OS was similar without significant difference (42.4% vs. 27.3%, P = 0.197).
Conclusion: RAMPS is a safe and oncologically feasible procedure in left-sided pancreatic cancer by obtaining a successful negative tangential margin and radical lymph node dissection. The authors suggest it could also be useful for local control, especially for the limited left-sided pancreatic cancer without nodal invasion.
Methods: From January 2007 to February 2015, a total of 30 RAMPS and 19 conventional distal pancreatectomy (DP) cases were enrolled. The demographics, perioperative and survival outcomes were compared according to the type of surgery.
Results: The mean operative time, blood loss and length of hospital stay were similar between 2 groups. Morbidities were reported in 14 cases of RAMPS (46.7%) and 8 cases of DP (42.1%) (P = 0.777). The rate of negative tangential margin (96.2%) and the number of harvested lymph nodes (mean ± standard deviation, 21.5 ± 8.3) were significantly higher in RAMPS group (P = 0.011, P = 0.003, respectively). In terms of survival outcomes, there was no significant difference in regard to the overall 3-year disease-free survival (DFS; 30.4% in RAMPS vs. 35.0% in DP, P = 0.354) or overall survival (OS; 29.9% vs. 29.4%, P = 0.429) between the 2 groups. After exclusion of cases with nodal invasion, however, the RAMPS group had a longer DFS than the DP group (55.6% vs. 27.3%, P = 0.048) although OS was similar without significant difference (42.4% vs. 27.3%, P = 0.197).
Conclusion: RAMPS is a safe and oncologically feasible procedure in left-sided pancreatic cancer by obtaining a successful negative tangential margin and radical lymph node dissection. The authors suggest it could also be useful for local control, especially for the limited left-sided pancreatic cancer without nodal invasion.
목차
INTRODUCTION
METHODS
RESULTS
DISCUSSION
REFERENCES
참고문헌 (14)
참고문헌 신청
[학술지(정기간행물)] - Christein JD. / 2005 / Distal pancreatectomy for resectable adenocarci noma of the body and tail of the pancreas / J Gastrointest Surg 9 : 922 ~ 927
[학술지(정기간행물)] - Shoup M. / 2003 / Is extended resection for adenocarcinoma of the body or tail of the pancreas justified? / J Gastrointest Surg 7 : 946 ~ 952
[학술지(정기간행물)] - Niederhuber JE. / 1995 / The National Cancer Data Base report on pancreatic cancer / Cancer 76 : 1671 ~ 1677
[학술지(정기간행물)] - Andren-Sandberg A. / 1999 / Technical aspects of left-sided pancreatic resection for cancer / Dig Surg 16 : 305 ~ 312
[학술지(정기간행물)] - Strasberg SM. / 2003 / Radical antegrade modular pancreatosplenectomy / Surgery 133 : 521 ~ 527
[학술지(정기간행물)] - Shoup M. / 2003 / Is extended resection for adenocarcinoma of the body or tail of the pancreas justified? / J Gastrointest Surg 7 : 946 ~ 952
[학술지(정기간행물)] - Niederhuber JE. / 1995 / The National Cancer Data Base report on pancreatic cancer / Cancer 76 : 1671 ~ 1677
[학술지(정기간행물)] - Andren-Sandberg A. / 1999 / Technical aspects of left-sided pancreatic resection for cancer / Dig Surg 16 : 305 ~ 312
[학술지(정기간행물)] - Strasberg SM. / 2003 / Radical antegrade modular pancreatosplenectomy / Surgery 133 : 521 ~ 527
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UCI(KEPA) : I410-ECN-0101-2017-514-001019610