지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.8
- 수록면
- 226 - 231 (6page)
- DOI
- 10.15188/kjopp.2018.08.32.4.226
이용수
초록· 키워드
오류제보하기
Chijabaegpi-tang (CHG) is an oriental herbal medicine that has been used for its various pharmacological effects, which include anti-inflammatory, anti-oxidant and immunoregulation activities. In the present study, we investigated which skin inflammations are involved in the TNF-α/IFNγ-induced HaCaT cells. We investigated the suppressive effect of CHG on TNF-α/IFNγ-induced HaCaT cell production of the following chemokines: macrophage-derived chemokine (MDC)/CCL22; regulated on activation, normal T-cell expressed and secreted (RANTES)/CCL5; and interleukin-8 (IL-8); thymus and activation-regulated chemokine (TARC)/CCL17. The pre-treatment of HaCaT cells with CHG suppressed TNF-α/IFNγ-induced nuclear transcription factor kappa-B (NF-κB). In addition, CHG inhibited TNF-α/IFNγ-induced phosphorylation of ERK and p38. TNF-α/IFNγ suppressed the expression of skin barrier proteins, including filaggrin (FLG), Involucrin (IVL) and loricrin (LOR). By contrast, CHG restored the expression of FLG, IVL and LOR. Taken together, our findings suggest that CHG could be a therapeutic agent for prevention of skin disease, including atopic dermatitis.
목차
서론
재료 및 방법
결과
고찰
References
참고문헌 (21)
참고문헌 신청
[학술지(정기간행물)] - Howlett S / 1999 / Emotional dysfunction, child-family relationships and childhood atopic dermatitis / Br J Dermatol 140 : 381 ~ 384
[학술지(정기간행물)] - Foolad N / 2012 / Effect of nutrient supplementation on atopic dermatitis in children / Arch Dermatol 17 : 1 ~ 6
[학술지(정기간행물)] - Leung DY / 2000 / Atopic dermatitis: new insights and opportunities for therapeutic intervention / J Allergy Clin Immunol 105 : 860 ~ 876
[학술지(정기간행물)] - Mohan GC / 2015 / Comparison of dermatology and allergy guidelines for atopic dermatitis management / JAMA Dermatol 151 : 1009 ~ 1013
[학술지(정기간행물)] - Lyons JJ / 2015 / Atopic dermatitis in children: clinical features, pathophysiology, and treatment / Immunol Allergy Clin North Am 35 : 161 ~ 183
[학술지(정기간행물)] - Foolad N / 2012 / Effect of nutrient supplementation on atopic dermatitis in children / Arch Dermatol 17 : 1 ~ 6
[학술지(정기간행물)] - Leung DY / 2000 / Atopic dermatitis: new insights and opportunities for therapeutic intervention / J Allergy Clin Immunol 105 : 860 ~ 876
[학술지(정기간행물)] - Mohan GC / 2015 / Comparison of dermatology and allergy guidelines for atopic dermatitis management / JAMA Dermatol 151 : 1009 ~ 1013
[학술지(정기간행물)] - Lyons JJ / 2015 / Atopic dermatitis in children: clinical features, pathophysiology, and treatment / Immunol Allergy Clin North Am 35 : 161 ~ 183
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
피부각질세포에서 치자백피탕(梔子柏皮湯)의 아토피 피부염 개선효과
동의생리병리학회지
2018 .01
-
Mechanism of Macrophage-Derived Chemokine/CCL22 Production by HaCaT Keratinocytes
Annals of Dermatology
2015 .01
-
Ethanolic extracts of artemisia apiacea Hance improved atopic dermatitis-like skin lesions and suppressed TNF-α/IFN-γ–induced proinflammatory chemokine production in HaCaT cells
한국실험동물학회 학술발표대회 논문집
2019 .07
-
Anti-inflammatory Activity of Fucoidan with Blocking NF-κB and STAT1 in Human Keratinocytes Cells
Natural Product Sciences
2015 .09
-
HaCaT 세포에서 Lactobacillus 혼합배양액 추출물이 아토피관련 케모카인 발현에 미치는 효과
Korean Journal of Acupuncture
2017 .01
-
Inhibition of Chitinase-3-like-1 by K284-6111 Reduces Atopic Skin Inflammation via Repressing Lactoferrin
Immune Network
2021 .06
-
Species Specific Antiviral Activity of Porcine Interferon-α8 (IFNα8)
Immune Network
2017 .12
-
Aster glehni Ethanol Extract Inhibits Inflammatory Responses Regulating Skin Barrier Molecules in Human Keratinocytes
Natural Product Sciences
2024 .12
-
Schefflera farinosa J.J.Sm. inhibits TNF-α/IFN-γ-induced chemokine production via blockade of NF-κB activation in human epidermal keratinocytes
한국실험동물학회 학술발표대회 논문집
2020 .02
-
Optimization of Cytokine Milieu to Reproduce Atopic Dermatitis-related Gene Expression in HaCaT Keratinocyte Cell Line
Immune Network
2018 .04
-
山白菊 열수추출물이 HaCaT 피부각질세포에서 미치는 항염증 효과
한방안이비인후피부과학회지
2022 .05
-
Korean Red Ginseng improves atopic dermatitis-like skin lesions by suppressing expression of proinflammatory cytokines and chemokines in vivo and in vitro
Journal of Ginseng Research
2017 .04
-
Prognostic value of TNF-a-308 and IFN-g-874 single nucleotide polymorphisms and their plasma levels in patients with aplastic anemia
Blood Research
2020 .01
-
Saccharina japonica Attenuates the Allergic Inflammation in vivo and in vitro
대한의생명과학회지
2022 .12
-
Effects of Ethanol Extracts of Anemarrhena asphodeloides on Skin Barrier Function by Inflammation
한방안이비인후피부과학회지
2018 .01
-
Analysis of the Apoptotic Mechanisms of Snake Venom Toxin on Inflammation-induced HaCaT Cell-line
대한침구의학회지
2017 .01
-
TNF-α로 유도된 HaCaT 각질형성세포의 염증반응에서 해죽순의 항염증 효과
대한본초학회지(본초분과학회지)
2019 .01
-
황련 추출물의 아토피피부염 유발 생쥐에서 피부손상 완화 효과
동의생리병리학회지
2019 .01
-
Innate Immune Response to Viral Infections in Primary Bronchial Epithelial Cells is Modified by the Atopic Status of Asthmatic Patients
Allergy, Asthma & Immunology Research
2018 .01
-
Synergistic Inhibition of Tumor Necrosis Factor-Alpha-Stimulated Pro-Inflammatory Cytokine Expression in HaCaT Cells by a Combination of Rapamycin and Mycophenolic Acid
Annals of Dermatology
2015 .01
이 논문의 저자 정보
이 논문과 함께 이용한 논문
아로마테라피를 활용한 청소년의 건강 효과 연구 : 여고생의 생리통을 중심으로
홍명희
한국엔터테인먼트산업학회논문지
2019
.02
스마트폰 과사용이 청소년의 건강과 학업에 미치는 영향 : 2017년 청소년건강행태온라인조사 자료를 이용하여
문종훈
,
전민재
,
송이슬
한국엔터테인먼트산업학회논문지
2019
.02
청소년의 자아존중감이 자살생각에 미치는 영향 : 대인관계스트레스 유형에 따른 매개효과검정
김한솔
,
염동문
,
장유미
사회과학연구
2019
.01
올리고 펩타이드 유도체의 합성과 생리활성에 관한 연구
김보미
한국산학기술학회 논문지
2018
.12
아토피 피부염 모델에 대한 β-1,3/1,6-glucan과 Lactobacillus plantarum LM1004의 면역 조절 효과
김인성
,
김성학
,
김정아
외 7명
생명과학회지
2018
.01
최근 본 자료
댓글(0)
0