지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
오류제보하기
The simple and effective analytical method for the quality control of a novel scalp tonic formulation has been developed and optimized in terms of HPLC conditions and sample preparation method, meanwhile, the optimization of preparation condition was using response surface methodology (RSM) based on central composite design (CCD). Oleanolic acid was selected as marker compound because of its bioactivities for alopecia therapy. The developed analytical method and extraction condition were successfully qualified. Coefficient of determination (r²) for the calibration was 0.9997 with a line passing through the origin point in the range of 0.1-100 mg/mL. The limit of detection (LOD) and the limit of quantitation (LOQ) were 17.5ng/mL and 55.0 ng/mL, respectively. The intra-day and inter-day precision of the method were 0.5-1.4 % and 0.7-1.8 % in relative standard deviation, respectively, while those accuracy were 99.5-100.9 % and 100.0- 102.2 %, respectively. The repeatability of oleanolic acid in samples ranged of 0.3-1.9 % based on peak area and 0.3-0.7 % for retention time. Recoveries from samples were 95.0-99.4 % with lower than 1.8 % in relative standard deviation. Overall, the developed analytical method will be used for quality control of this commercial scalp tonic products successfully.
목차
Abstract
1. Introduction
2. Materials and Methods
3. Results and Discussion
4. Conclusions
References
참고문헌 (29)
참고문헌 신청
L. H. Su, L. S. Chen, and H. H. Chen, J. Am. Acad. Dermatol., 69(2), 69-77 (2013).
R. C. Gathers and M. G. Mahan, J. Clin. Aesthet. Dermatol., 7, 26-29 (2014).
M. Alfonso, H. Richter-Appelt, A. Tosti, M. S. Viera, and M. Garcia, Curr. Med. Res.Oper., 21, 1829-1836 (2005).
S. J. Yun, J.-W. Lee, H.-J. Yoon, S. S. Lee, S.-Y. Kim, J.-B. Lee, S.-C. Lee, Y.-H. Won, and S.-J. Kim, J. Dermatol., 34, 451-455 (2007).
P. Mirmirani, Maturitas, 74(2), 119-122 (2013).
R. C. Gathers and M. G. Mahan, J. Clin. Aesthet. Dermatol., 7, 26-29 (2014).
M. Alfonso, H. Richter-Appelt, A. Tosti, M. S. Viera, and M. Garcia, Curr. Med. Res.Oper., 21, 1829-1836 (2005).
S. J. Yun, J.-W. Lee, H.-J. Yoon, S. S. Lee, S.-Y. Kim, J.-B. Lee, S.-C. Lee, Y.-H. Won, and S.-J. Kim, J. Dermatol., 34, 451-455 (2007).
P. Mirmirani, Maturitas, 74(2), 119-122 (2013).
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Quality control for a scalp tonic product containing pulsatillae radix extract by LC-MS/MS
한국분석과학회 학술대회
2016 .11
-
Oleanolic Acids Inhibit Vascular Endothelial Growth Factor Receptor 2 Signaling in Endothelial Cells: Implication for Anti-Angiogenic Therapy
Molecules and Cells
2018 .08
-
Analysis of erectile dysfunction drugs and their analogues in counterfeit drugs and herbal medicines by LC-ESI-MS/MS
분석과학
2016 .08
-
Optimization of an extraction method for the simultaneous quantification of six active compounds in the aril part of Orostachys japonicus using HPLC-UV
분석과학
2021 .08
-
사료 중 유기산 7종 동시분석법 개발 및 유통 사료의 모니터링
분석과학
2016 .08
-
Characteristic of Microbiome in Scalp Skin of Healthy and Alopecia Subjects
한국미생물학회 학술대회논문집
2021 .08
-
LC-MS/MS Method for Simultaneous Analysis of Growth Hormone-Releasing Peptides and Secretagogues in Human Urine
Mass Spectrometry Letters
2016 .09
-
Optimization of HPLC Method for the Analysis of Crotamiton using Response Surface Methodology
한국분석과학회 학술대회
2015 .11
-
방사광 동결 미세 단층촬영을 이용한 사람 두피 조직의 3차원 구조분석
새물리
2019 .04
-
Developing an analytical approach with HPLC-UV of hyaluronic acid in health functional food (HFF) products
한국분석과학회 학술대회
2023 .11
-
Determination of methamphetamine and amphetamine enantiomers in human urine by chiral stationary phase liquid chromatography-tandem mass spectrometry
분석과학
2019 .10
-
Determination of Corticosteroids in Moisturizers by LC-MS/MS
Mass Spectrometry Letters
2016 .03
-
시판막장의 품질 특성 및 항산화성
한국식품조리과학회지
2015 .01
-
Analysis of tetracyclines in shrimp samples based on a two-step extraction approach prior to high-performance liquid chromatography
분석과학
2024 .08
-
고성능 액체크로마토그래피를 이용한 에키네시아의 caffeic acid 유도체 화합물 함량분석
생활과학연구논총
2020 .01
-
Development of simple HPLC-UV method for discrimination of Adenophorae Radix
분석과학
2017 .04
-
Simultaneous determination of illegal galactagogue adulterants in supplement diets by LC-MS/MS
분석과학
2018 .08
-
당류/당알코올류 HPLC 분석용 CNT 컬럼 개발 및 분석법 최적화 연구
한국분석과학회 학술대회
2022 .11
-
Development of the HPLC analytical method of two components in SH and CO mixture using HPLC-ELSD
한국분석과학회 학술대회
2018 .11
-
Development and validation of an analytical method for the quantification of 2,6-diisopropylnaphthalene in agricultural products using GC-MS/MS
분석과학
2021 .02
이 논문의 저자 정보
최근 본 자료
댓글(0)
0