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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2015.1
- 수록면
- 87 - 93 (7page)
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초록· 키워드
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Background/Aims: To analyze the effect of short-term supportive temporary partial enteral nutrition therapy for treating severe pediatric Crohn’s disease (CD). Methods: We conducted a prospective, open-label study in pediatric patients with CD (n=78) from January 2007 to December 2011. The CD patients were divided into three groups according to disease severity (mild, moderate, and severe). Seventeen patients with severe CD received short-term partial enteral nutrition (SPEN) in addition to their general diet for 4 weeks after the induction of remission with medical treatment.
This SPEN group was further divided into two groups by age (<13 years, ≥13 years). Nutritional parameters and Pediatric Crohn’s Disease Activity Index scores were analyzed at the initial enrollment and following 1 year of treatment for all groups. Results: Nutritional status improved substantially after 1 year of treatment in the severe CD group. Nutritional status in the SPEN group improved considerably more than that in the non-SPEN group. Additionally, the <13-year-old group demonstrated better nutritional status improvement than the ≥13-year-old group. Conclusions: SPEN may be effective in pediatric patients with severe CD for improving nutritional status and moderating disease severity.
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참고문헌 (31)
참고문헌 신청
Ludvigsson JF / 2004 / Elemental versus polymeric enteral nutrition in paediatric Crohn’s disease: a multicentre randomized controlled trial / Acta Paediatr 93:327~335
Grogan JL / 2012 / Enteral feeding therapy for newly diagnosed pediatric Crohn’s disease: a double-blind randomized controlled trial with two years follow-up / Inflamm Bowel Dis 18:246~253
Verma S / 2000 / Polymeric versus elemental diet as primary treatment in active Crohn’s disease: a randomized, double-blind trial / Am J Gastroenterol 95:735~739
Hartman C / 2008 / Nutritional supplementation with polymeric diet enriched with transforming growth factor-beta 2 for children with Crohn’s disease / Isr Med Assoc J 10:503~507
Conklin LS / 2010 / Nutritional considerations in pediatric inflammatory bowel disease / Expert Rev Gastroenterol Hepatol 4:305~317
Grogan JL / 2012 / Enteral feeding therapy for newly diagnosed pediatric Crohn’s disease: a double-blind randomized controlled trial with two years follow-up / Inflamm Bowel Dis 18:246~253
Verma S / 2000 / Polymeric versus elemental diet as primary treatment in active Crohn’s disease: a randomized, double-blind trial / Am J Gastroenterol 95:735~739
Hartman C / 2008 / Nutritional supplementation with polymeric diet enriched with transforming growth factor-beta 2 for children with Crohn’s disease / Isr Med Assoc J 10:503~507
Conklin LS / 2010 / Nutritional considerations in pediatric inflammatory bowel disease / Expert Rev Gastroenterol Hepatol 4:305~317
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