지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한소아소화기영양학회 Pediatric Gastroenterology, Hepatology & Nutrition Pediatric Gastroenterology, Hepatology & Nutrition 제20권 제3호
- 발행연도
- 2017.1
- 수록면
- 178 - 185 (8page)
이용수
초록· 키워드
오류제보하기
Purpose: To evaluate the outcomes of a hybrid prophylactic strategy to prevent cytomegalovirus (CMV) disease in pediatric liver transplantation (LT) patients.Methods: CMV DNAemia was regularly monitored by quantitative nucleic acid amplification test (QNAT) and was quantified in all children. CMV infection and disease were defined according to the International Consensus Guidelines. The hybrid strategy against CMV infection consisted of universal 3-week prophylaxis and preemptive treatment of intravenous ganciclovir regardless of the recipient’s serostatus. Results: A total of 143 children who underwent living donor LT were managed using the hybrid strategy. The overall incidence of CMV infection by QNAT was 48.3% (n=69/143). The highest CMV DNAemia positivity was observed in 49.2% (n=60/122) of children in the D+/R+ group, followed by 46.7% (n=7/15) in the D+/R− group. CMV disease was noted in 26.1% (n=18/69) patients. Forty-three (62.3%) children had undergone preemptive therapy consisting of intravenous ganciclovir. No symptomatic patients developed tissue-invasive disease, resulting in no CMV-asso-ciated mortality.Conclusion: The incidence of CMV infection was high in pediatric LT patients despite the hybrid strategy. However, tissue-invasive disease in pediatric LT did not occur.
목차
등록된 정보가 없습니다.
참고문헌 (21)
참고문헌 신청
Bedel AN / 2012 / Retrospective review of the incidence of cytomegalovirus infection and disease after liver transplantation in pediatric patients:comparison of prophylactic
Bowman JS / 1991 / OKT3 and viral disease in pediatric liver transplant recipients / Clin Transplant 5 : 294 ~ 300
Danziger-Isakov L / 2014 / Current prevention strategies against cytomegalovirus in the studies in pediatric liver transplantation (SPLIT) centers / Am J Transplant 14 :
Demetris A / 2000 / Update of the international banff schema for liver allograft rejection: working recommendations for the histopathologic staging and reporting of chronic
Fishman JA / 2007 / Infection in solid-organ transplant recipients / N Engl J Med 357 : 2601 ~ 2614
Bowman JS / 1991 / OKT3 and viral disease in pediatric liver transplant recipients / Clin Transplant 5 : 294 ~ 300
Danziger-Isakov L / 2014 / Current prevention strategies against cytomegalovirus in the studies in pediatric liver transplantation (SPLIT) centers / Am J Transplant 14 :
Demetris A / 2000 / Update of the international banff schema for liver allograft rejection: working recommendations for the histopathologic staging and reporting of chronic
Fishman JA / 2007 / Infection in solid-organ transplant recipients / N Engl J Med 357 : 2601 ~ 2614
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Cytomegalovirus Infection in Pediatric Renal Transplant Recipients: A Single Center Experience
Childhood Kidney Diseases
2017 .01
-
Diagnostic Usefulness of Cytomegalovirus (CMV)- Specific T Cell Immunity in Predicting CMV Infection after Kidney Transplantation: A Pilot Proof-of- Concept Study
Infection and Chemotherapy
2015 .01
-
A Case Treated with Extracorporeal Membrane Oxygenation for Disseminated Cytomegalovirus Infection after Liver Transplantation
Clinical Transplantation and Research
2017 .01
-
Cytomegalovirus Infection after Renal Transplantation: Occurrence, Clinical Features, and the Cutoff for Antigenemia in a University Hospital in Brazil
Infection and Chemotherapy
2017 .01
-
Laboratory diagnostic testing for cytomegalovirus infection in solid organ transplant patients
Clinical Transplantation and Research
2022 .03
-
Human Cytomegalovirus Infection in Solid-Organ Transplantation
JOURNAL OF BACTERIOLOGY AND VIROLOGY
2015 .03
-
Emergency gastrointestinal tract operation associated with cytomegalovirus infection
Annals of Surgical Treatment and Research
2023 .02
-
Clinical Usefulness of Monitoring Cytomegalovirus-Specific Immunity by Quantiferon-CMV in Pediatric Allogeneic Hematopoietic Stem Cell Transplantation Recipients
Annals of Laboratory Medicine
2017 .01
-
Prevention of Cytomegalovirus Infection in Solid Organ Transplant Recipients: Guidelines by the Korean Society of Infectious Diseases and the Korean Society for Transplantation
Infection and Chemotherapy
2024 .03
-
Liver Abscess caused by Cytomegalovirus in a Patient with Acquired Immunodeficiency Syndrome
Infection and Chemotherapy
2022 .12
-
Audiologic Status of Children with Confirmed Cytomegalovirus Infection: a Case Series
Journal of Korean Medical Science
2020 .01
-
Immunological Prediction of Cytomegalovirus (CMV) Replication Risk in Solid Organ Transplantation Recipients: Approaches for Regulating the Targeted Anti-CMV Prevention Strategies
Infection and Chemotherapy
2017 .01
-
Sensitivity of the Cytomegalovirus Antigenemia Assay to Diagnose Cytomegalovirus Retinitis
Infection and Chemotherapy
2016 .12
-
The Detailed Kinetics of Cytomegalovirus-specific T cell Responses after Hematopoietic Stem Cell Transplantation : 1 Year Follow-up Data
Immune Network
2018 .04
-
Recent advancements in the pediatric liver transplantation : A single-center study of 235 patients over 27 years
한국간담췌외과학회 학술대회지
2016 .04
-
Comparison of the Commercial QuantiFERON-CMV and Overlapping Peptide-based ELISPOT Assays for Predicting CMV Infection in Kidney Transplant Recipients
Immune Network
2017 .10
-
Two Cases of Cytomegalovirus Infection Developed in Pediatric Acute Lymphoblastic Leukemia Patients
Clinical Pediatric Hematology-Oncology
2019 .01
-
Disseminated Cytomegalovirus Infection and Protein Losing Enteropathy as Presenting Feature of Pediatric Patient with Crohn’s Disease
Pediatric Gastroenterology, Hepatology & Nutrition
2015 .01
-
Study on Patients without Underlying Chronic Liver Disease to Improve Survival Outcome in Pediatric Liver Transplantation
대한외과학회 학술대회 초록집
2020 .11
-
Breast Milk-Transmitted Cytomegalovirus Infection in Preterm Infants
Neonatal medicine
2018 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0