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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.1
- 수록면
- 105 - 105 (1page)
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Since the first component of Hippo signaling, Wts in Drosophila, was identified in 1995, the progress of Hippo signaling studies has been very slow initially. However, after the findings suggesting that the core kinase pathway established in Drosophila was evolutionarily conserved in metazoans for the determination of organ size around 2008, the number of publications related to Hippo signaling has grown exponentially. Identification of molecular mechanisms underlying Hippo signaling response to intrinsic cues, such as cell-cell contact and mechanotransduction, as well as extrinsic cues, such as nutrients and soluble factors, has been one of the key topics of Hippo signaling. In the beginning, the role of Hippo signaling in the regulation of cell proliferation, organ size determination and tumorigenesis was mainly studied. However, the study of Hippo signaling expanded recently to unexpected biological phenomena such as tissue regeneration, innate immunity and miRNA biogenesis. Editors of BMB Reports thought that it was timely and informative to review the status of Hippo signaling to introduce the topic to researchers outside of this field. As an editor of BMB Reports, I invited seven researchers, who are currently working in Korea on different aspects of Hippo signaling, to submit minireviews.
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Upstream paths for Hippo signaling in Drosophila organ development
BMB Reports
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Regulation of the Hippo signaling pathway by ubiquitin modification
BMB Reports
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The history and regulatory mechanism of the Hippo pathway
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Regulation of Hippo signaling by actin remodeling
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The role of extracellular biophysical cues in modulating the Hippo-YAP pathway
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HiPPO 메모리 프레임워크를 사용한 궤적 기반 모방학습
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Regulation and Regulators of the Hippo-YAP/TAZ Pathway
한국생물공학회 학술대회
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A novel role of Hippo-Yap/TAZ signaling pathway in lymphatic vascular development
BMB Reports
2021 .01
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Hippo-YAP/TAZ signaling in angiogenesis
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Interacting network of Hippo, Wnt/β-catenin and Notch signaling represses liver tumor formation
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The potential role of YAP in head and neck squamous cell carcinoma
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2020 .08
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Clinical implications of the Hippo-YAP pathway in multiple cancer contexts
BMB Reports
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Insulin receptor substrate 2: a bridge between Hippo and AKT pathways
BMB Reports
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Dishevelling Wnt and Hippo
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Deubiquitinase YOD1: the potent activator of YAP in hepatomegaly and liver cancer
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Effect of PFKFB3 on YAP-TEAD Interaction
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EMI Issues in Pseudo-Differential Signaling for SDRAM Interface
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FGF signaling: diverse roles during cochlear development
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