지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한정신약물학회 Clinical Psychopharmacology and Neuroscience Clinical Psychopharmacology and Neuroscience 제16권 제2호
- 발행연도
- 2018.1
- 수록면
- 214 - 217 (4page)
이용수
초록· 키워드
오류제보하기
Objective: In our previous study, it has been reported that valproic acid (VPA) effects gliogenesis and increases the number of glial precursor cells during the early postnatal period. However there is no specific report that whether this process is going on up to the age of mature brain development and the consequence effect of this ongoing gliogenesis process. Methods: As an ongoing study, using Immunoblotting analysis, we checked the level of glial protein and glial-derived factor markers in the frontal cortex of a rat brain at postnatal day (PND) 21. Results: The finding of the study suggests that, in the VPA group (p＜0.05), early exposure elicited significantly to increase the expression level of glial protein cells at PND 21 in the frontal cortex of rat brain. Conclusion: Therefore we suggest that, alter gliogenesis and abnormal number of glial cells modulate the neurobiological dysfunction and induces the risk of neurodevelopmental disorders.
목차
등록된 정보가 없습니다.
참고문헌 (18)
참고문헌 신청
Nedergaard M / 1994 / Direct signaling from astrocytes to neurons in cultures of mammalian brain cells / Science 263:1768~1771
Tamanna Jahan Mony / 2016 / Valproic Acid Exposure during Early Postnatal Gliogenesis Leads to Autistic-like Behaviors in Rats / Clinical Psychopharmacology and Neuroscience 14(4):338~344
Kornack DR / 2001 / Cell proliferation without neurogenesis in adult primate neocortex / Science 294:2127~2130
Rajkowska G / 2007 / Gliogenesis and glial pathology in depression / CNS Neurol Disord Drug Targets 6:219~233
Lee HJ / 2016 / Valproic acid stimulates proliferation of glial precursors during cortical gliogenesis in developing rat / Dev Neurobiol 76:780~798
Tamanna Jahan Mony / 2016 / Valproic Acid Exposure during Early Postnatal Gliogenesis Leads to Autistic-like Behaviors in Rats / Clinical Psychopharmacology and Neuroscience 14(4):338~344
Kornack DR / 2001 / Cell proliferation without neurogenesis in adult primate neocortex / Science 294:2127~2130
Rajkowska G / 2007 / Gliogenesis and glial pathology in depression / CNS Neurol Disord Drug Targets 6:219~233
Lee HJ / 2016 / Valproic acid stimulates proliferation of glial precursors during cortical gliogenesis in developing rat / Dev Neurobiol 76:780~798
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Valproic Acid Exposure during Early Postnatal Gliogenesis Leads to Autistic-like Behaviors in Rats
Clinical Psychopharmacology and Neuroscience
2016 .01
-
Phagocytic Roles of Glial Cells in Healthy and Diseased Brains
Biomolecules & Therapeutics(구 응용약물학회지)
2018 .01
-
Stress Changes the Spatial Arrangement of Neurons and Glial Cells of Medial Prefrontal Cortex and Sertraline and Curcumin Prevent It
PSYCHIATRY INVESTIGATION
2015 .01
-
The Neuro-Protective Effect of the Methanolic Extract of Perilla frutescens var. japonica and Rosmarinic Acid against H<sub>2</sub>O<sub>2</sub>-Induced Oxidative Stress in C6 Glial Cells
Biomolecules & Therapeutics(구 응용약물학회지)
2016 .01
-
A Single Intraperitoneal Injection of Endotoxin Changes Glial Cells in Rats as Revealed by Positron Emission Tomography Using [<sup>11</sup>C]PK11195
Nuclear medicine and molecular imaging : NMMI
2018 .01
-
Valproic Acid Exposure of Pregnant Rats During Organogenesis Disturbs Pancreas Development in Insulin Synthesis and Secretion of the Offspring
Toxicological Research
2018 .04
-
신경아교세포와 조현병
생물정신의학
2015 .01
-
Dual mechanisms for the regulation of brain-derived neurotrophic factor by valproic acid in neural progenitor cells
The Korean Journal of Physiology & Pharmacology
2018 .11
-
A study on glial scar formation in spinal cord injury model
한국실험동물학회 학술발표대회 논문집
2018 .07
-
Sequential Activation of AMPA Receptors and Glial Cells in a Pain Model of Lumbar Spine Disc Herniation
Annals of Rehabilitation Medicine
2020 .01
-
Changes in glial and blood-brain barrier on effective transcranial direct current stimulation (tDCS) after transient cerebral ischemia
한국실험동물학회 학술발표대회 논문집
2019 .01
-
Laser Acupuncture Improves Behavioral Disorders and Brain Oxidative Stress Status in the Valproic Acid Rat Model of Autism
Journal of Acupuncture & Meridian Studies
2015 .01
-
Dextromethorphan Protect the Valproic Acid Induced Downregulation of Neutrophils in Patients with Bipolar Disorder
Clinical Psychopharmacology and Neuroscience
2020 .01
-
성상세포유래 신경영양인자의 자가생성 촉진에 의한 장기적 운동능력 향상 효과
약학회지
2016 .01
-
Nutraceutical emulsion containing valproic acid (NE-VPA): a drug delivery system for reversion of seizures in zebrafish larvae epilepsy model
Journal of Pharmaceutical Investigation
2017 .09
-
Histological study of the effect of cellular phone electromagnetic wave on the neonatal rat cerebellar cortex
예방수의학회지
2018 .03
-
Production of transgenic pigs using a pGFAP-CreERT2/EGFPLoxP inducible system for central nervous system disease models
Journal of Veterinary Science
2018 .05
-
A Role of Serum-Based Neuronal and Glial Markers as Potential Predictors for Distinguishing Severity and Related Outcomes in Traumatic Brain Injury
대한신경외과학회지
2015 .01
-
Caffeic Acid의 항산화 활성 및 Amyloid beta와 LPS에 의한 C6 Glial 세포의 산화적 스트레스 보호 효과
생약학회지(Korean Journal of Pharmacognosy)
2015 .06
-
Roles of Valproic Acid in Improving Radiation Therapy for Glioblastoma: a Review of Literature Focusing on Clinical Evidence
Asian Pacific journal of cancer prevention : APJCP
2016 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0