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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한정신약물학회 Clinical Psychopharmacology and Neuroscience Clinical Psychopharmacology and Neuroscience 제16권 제3호
- 발행연도
- 2018.1
- 수록면
- 262 - 266 (5page)
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Objective: Unipolar and bipolar depression (UD and BD) differ strikingly in respect to neurobiology, course and management, but their apparent clinical similarity often leads to misdiagnosis resulting in chronicity of course and treatment failure. In this study we have tried to assess whether UD and BD can be differentiated on the basis of their dissociative symptoms. Methods: Thrty-six UD patients and 35 BD patients in active episodes, without any psychiatric comorbidity were selected from outpatient department and compared for depressive and dissociative symptoms using Hamilton Depression Rating Scale and Dissociative Experience Scale-II (DES-II). Results: We found that thought the two groups didn’t differ in terms of the socio-demographic or clinical variables, BD group had significantly higher dissociative experience (U=343, p=0.001) than UD and the difference remained significant even after adjusting for the confounding factors. Conclusion: Our study shows that dissociative symptoms are significantly more prevalent in the depressive episodes of bipolar affective disorder as compared to the UD and can be an important tool in differentiating between the two disorders with very similar clinical profile. The difference can be measured using a simple self-report questionnaire like DES-II.
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참고문헌 (24)
참고문헌 신청
Bowden CL / 2001 / Strategies to reduce misdiagnosis of bipolar depression / Psychiatr Serv 52:51~55
Smith DJ / 2010 / Is underdiagnosis the main pitfall when diagnosing bipolar disorder? Yes / BMJ 340:c854
Angst J / 2007 / The bipolar spectrum / Br J Psychiatry 190:189~191
Koukopoulos A / 2014 / DSM-5 criteria for depression with mixed features: a farewell to mixed depression / Acta Psychiatr Scand 129:4~16
Spiegel D / 2011 / Dissociative disorders in DSM-5 / Depress Anxiety 28:E17~E45
Smith DJ / 2010 / Is underdiagnosis the main pitfall when diagnosing bipolar disorder? Yes / BMJ 340:c854
Angst J / 2007 / The bipolar spectrum / Br J Psychiatry 190:189~191
Koukopoulos A / 2014 / DSM-5 criteria for depression with mixed features: a farewell to mixed depression / Acta Psychiatr Scand 129:4~16
Spiegel D / 2011 / Dissociative disorders in DSM-5 / Depress Anxiety 28:E17~E45
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