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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.1
- 수록면
- 81 - 85 (5page)
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초록· 키워드
오류제보하기
The efficacy of intravesical onabotulinumtoxinA (BTXA) in the treatment of overactive bladder (OAB) has been well documented.
The use of BTXA injection in orthotopic neobladders is yet to be studied. We present 4 cases of patients injected with intravesical BTXA for overactive orthotopic ileal neobladder. We recorded patient demographics, presenting and follow-up symptoms, urodynamic profiles, and Patient Global Impression of Improvement (PGI-I) scores. The 4 patients reported varying degrees of subjective improvements in the symptoms, including urgency, urge incontinence, and pad usage. Mean followup duration was 8.3 months (range, 5–14 months). Average PGI-I score was 3 (“a little better”) (range, 2–4). To our knowledge, the current study is the first case series examining BTXA injection for orthotopic neobladder overactivity. BTXA injection yielded varying degrees of objective and subjective improvements, without significant complications. Intravesical BTXA injection is feasible and may be considered as a potential treatment alternative for OAB in orthotopic neobladders, although further study is warranted.
목차
등록된 정보가 없습니다.
참고문헌 (10)
참고문헌 신청
Madersbacher S / 2002 / Long-term voiding pattern of patients with ileal orthotopic bladder substitutes / J Urol 167:2052~2057
Yalcin I / 2003 / Validation of two global impression questionnaires for incontinence / Am J Obstet Gynecol 189:98~101
el-Bahnasawy MS / 2005 / Persistent and occasional nocturnal enuresis in orthotopic urinary diversion:is there a urodynamic difference? / BJU Int 96:1373~1377
Ciceron C / 2013 / Botulinum toxin type A injections in the augmented bladder after failure of augmentation enterocystoplasty in neurological patients:a retrospective multicenter study / Ann Phys Rehabil Med 56:e232~e233
Apostolidis A / 2006 / Proposed mechanism for the efficacy of injected botulinum toxin in the treatment of human detrusor overactivity / Eur Urol 49:644~650
Yalcin I / 2003 / Validation of two global impression questionnaires for incontinence / Am J Obstet Gynecol 189:98~101
el-Bahnasawy MS / 2005 / Persistent and occasional nocturnal enuresis in orthotopic urinary diversion:is there a urodynamic difference? / BJU Int 96:1373~1377
Ciceron C / 2013 / Botulinum toxin type A injections in the augmented bladder after failure of augmentation enterocystoplasty in neurological patients:a retrospective multicenter study / Ann Phys Rehabil Med 56:e232~e233
Apostolidis A / 2006 / Proposed mechanism for the efficacy of injected botulinum toxin in the treatment of human detrusor overactivity / Eur Urol 49:644~650
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