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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.1
- 수록면
- 784 - 789 (6page)
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초록· 키워드
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We aimed to examine the potential relationship between season of birth (SOB) and clinical characteristics in Korean patients with unipolar non-psychotic major depressive disorder (MDD). Using data from the Clinical Research Center for Depression (CRESCEND) study in South Korea, 891 MDD patients were divided into two groups, those born in spring/summer (n=457) and those born in autumn/winter (n=434). Measurement tools comprising the Hamilton Depression Rating Scale, Hamilton Anxiety Rating Scale, Brief Psychiatric Rating Scale, Scale for Suicidal Ideation, Clinical Global Impression of severity, Social and OccupationFunctional Assessment Scale, WHO Quality of Life assessment instrument-abbreviated version, Alcohol Use Disorder IdentificationTest, and Temperament and Character Inventory were used to evaluate depression, anxiety, overall symptoms, suicidal ideation, global severity, social function, quality of life, drinking, and temperament and character, respectively. Using independentt-tests for continuous variables and χ2 tests for discrete variables, the clinical characteristics of the two groups were compared.
MDD patients born in spring/summer were on average younger at onset of first depressive episode (t=2.084, p=0.038), had greater loss of concentration (χ2=4.589, p=0.032), and were more self-directed (t=2.256, p=0.025) than those born in autumn/winter.
Clinically, there was a trend for the MDD patients born in spring/summer to display the contradictory characteristics of more severe clinical course and less illness burden; this may have been partly due to a paradoxical effect of the 5-HT system.
목차
등록된 정보가 없습니다.
참고문헌 (50)
참고문헌 신청
Eisenberg DT / 2007 / Season of birth and dopamine receptor gene associations with impulsivity, sensation seeking and reproductive behaviors / PLoS One 2:e1216
Döme P / 2010 / Season of birth is significantly associated with the risk of completed suicide / Biol Psychiatry 68:148~155
Gonda X / 2012 / Star-crossed? The association of the 5-HTTLPR s allele with season of birth in a healthy female population, and possible consequences for temperament, depression and suicide / J Affect Disord 143:75~83
Antonsen JH / 2012 / Associations between season of birth and suicide: a brief review / Neuropsychopharmacol Hung 14:177~187
Davies G / 2003 / A systematic review and meta-analysis of Northern Hemisphere season of birth studies in schizophrenia / Schizophr Bull 29:587~593
Döme P / 2010 / Season of birth is significantly associated with the risk of completed suicide / Biol Psychiatry 68:148~155
Gonda X / 2012 / Star-crossed? The association of the 5-HTTLPR s allele with season of birth in a healthy female population, and possible consequences for temperament, depression and suicide / J Affect Disord 143:75~83
Antonsen JH / 2012 / Associations between season of birth and suicide: a brief review / Neuropsychopharmacol Hung 14:177~187
Davies G / 2003 / A systematic review and meta-analysis of Northern Hemisphere season of birth studies in schizophrenia / Schizophr Bull 29:587~593
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