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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2004.1
- 수록면
- 359 - 361 (3page)
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초록· 키워드
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Toll-like receptor (TLR) 3 is a member of the TLR family that confers innate immunity by recognizing viral pathogens. Herein, we report that the TLR3 isoform is expressed on human primary cells and cell lines. This isoform has 2,520 bp cDNAs compared to the 2,712 bp of full cDNA, is produced by deletion of an intron-like sequence within exon 4 and is co-expressed with wild type TLR3 in primary human astrocytes and glioblastoma cell lines. This finding suggests the TLR3 isoform in astrocytes may have a different immunological role for binding ligands during the immune response in brain.
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참고문헌 (10)
참고문헌 신청
/ 1998 / A family of human receptors structurally related to Drosophila Toll 95 : 588 ~ 593
/ 2000 / A Toll-like receptor recognizes bacterial DNA 408 : 740 ~ 745
/ 2000 / Differential alteration in intestinal epithelial cell expression of toll-like receptor 3 (TLR3) and TLR4 in inflammatory bowel disease 68 : 7010 ~ 7017
/ 2000 / The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between toll-like receptors 97 : 13766 ~ 13771
/ 2000 / Toll-like receptors: a growing family of immune receptors that are differentially expressed and regulated by different leukocytes 67 : 450 ~ 456
/ 2000 / A Toll-like receptor recognizes bacterial DNA 408 : 740 ~ 745
/ 2000 / Differential alteration in intestinal epithelial cell expression of toll-like receptor 3 (TLR3) and TLR4 in inflammatory bowel disease 68 : 7010 ~ 7017
/ 2000 / The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between toll-like receptors 97 : 13766 ~ 13771
/ 2000 / Toll-like receptors: a growing family of immune receptors that are differentially expressed and regulated by different leukocytes 67 : 450 ~ 456
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