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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.1
- 수록면
- 24 - 33 (10page)
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초록· 키워드
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Objectives : This study is to investigate the anti-inflammatory and anti-oxidant effects of Tongbi-san extract (TS) on RAW264.7 macrophages using by cell cytotoxicity, Nitric Oxide (NO) and Prostaglandin E2 (PGE2) production and 1,1-diphenyl-2-picryl ghdrazyl (DPPH) free radical scavenging capability.
Methods : Cell cytotoxicity was measured by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay. The production of NO was measured by Griess assay. The production of PGE2 was measured by immunoassay. And the anti-oxidant activity was measured by the DPPH method.
Results : TS did not increased significantly compared to the TS untreated group in the cell cytotoxicity. TS inhibited NO and PGE2 production in lipopolysaccharide-stimulated RAW 264.7 cells. TS had the DPPH free radical scavenging capability.
Conclusion : The anti-inflammtory and anti-oxidant effects of TS may be use for a treatment of anti-inflammatory diseases.
목차
등록된 정보가 없습니다.
참고문헌 (35)
참고문헌 신청
Cordell GA / 2014 / Phytochemistry and traditional medicine-the revolution continues / Phytochem Lett 10:28~40
World Health Organization / WHO Traditional medicine strategy
Torres-Rodrigues ML / 2016 / Anti-inflammatory and anti-oxidant effect of Calea urticifolia lyophilized aqueous extract on lipopolysaccharide-stimulated RAW 264.7macrophages / J Ethnopharmacol 188:266~274
Tracey KJ / 2002 / The inflammatory reflex / Nature 420:853~859
Chen X / 2015 / The anti-inflammatory activities of Ainsliaea fragrans Champ. extract and its components in lipopolysaccharide-stimulated RAW264.7 macrophages through inhibition of NF-kB pathway / J Ethnopharmacol 170:72~80
World Health Organization / WHO Traditional medicine strategy
Torres-Rodrigues ML / 2016 / Anti-inflammatory and anti-oxidant effect of Calea urticifolia lyophilized aqueous extract on lipopolysaccharide-stimulated RAW 264.7macrophages / J Ethnopharmacol 188:266~274
Tracey KJ / 2002 / The inflammatory reflex / Nature 420:853~859
Chen X / 2015 / The anti-inflammatory activities of Ainsliaea fragrans Champ. extract and its components in lipopolysaccharide-stimulated RAW264.7 macrophages through inhibition of NF-kB pathway / J Ethnopharmacol 170:72~80
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