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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 한국미생물생명공학회 Journal of Microbiology and Biotechnology Journal of Microbiology and Biotechnology 제19권 제2호
- 발행연도
- 2009.1
- 수록면
- 140 - 146 (7page)
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초록· 키워드
오류제보하기
MAPSI (Management and Analysis for Polyketide Synthase
Type I) has been developed to offer computational analysis
methods to detect type I PKS (polyketide synthase) gene
clusters in genome sequences. MAPSI provides a genome
analysis component, which detects PKS gene clusters by
identifying domains in proteins of a genome. MAPSI also
contains databases on polyketides and genome annotation
data, as well as analytic components such as new PKS
assembly and domain analysis. The polyketide data and
analysis component are accessible through Web interfaces
and are displayed with diverse information. MAPSI, which
was developed to aid researchers studying type I polyketides,
provides diverse components to access and analyze polyketide
information and should become a very powerful computational
tool for polyketide research. The system can be extended
through further studies of factors related to the biological
activities of polyketides.
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참고문헌 (25)
참고문헌 신청
Altschul, S. F. / 1990 / Basic local alignment search tool / J. Mol. Biol 215 : 403 ~ 410
Aparicio, J. F. / 1994 / Limited proteolysis and active-site studies of the first multienzyme component of the erythromycin-producing polyketide synthase / J. Biol. Chem 269
Broadhurst, R. W. / 2003 / The structure of docking domains in modular polyketide synthases / Chem. Biol 10 : 723 ~ 731
Cheng, Y. Q. / 2003 / Type I polyketide synthase requiring a discrete acyltransferase for polyketide biosynthesis / Proc. Natl. Acad. Sci. U.S.A. 100 : 3149 ~ 3154
Eddy, S. R. / 1999 / Profile hidden Markov models / Bioinformatics 14 : 755 ~ 763
Aparicio, J. F. / 1994 / Limited proteolysis and active-site studies of the first multienzyme component of the erythromycin-producing polyketide synthase / J. Biol. Chem 269
Broadhurst, R. W. / 2003 / The structure of docking domains in modular polyketide synthases / Chem. Biol 10 : 723 ~ 731
Cheng, Y. Q. / 2003 / Type I polyketide synthase requiring a discrete acyltransferase for polyketide biosynthesis / Proc. Natl. Acad. Sci. U.S.A. 100 : 3149 ~ 3154
Eddy, S. R. / 1999 / Profile hidden Markov models / Bioinformatics 14 : 755 ~ 763
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