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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.1
- 수록면
- 704 - 710 (7page)
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초록· 키워드
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Background: Cellulitis is a common bacterial infection of the superficial skin. Procalcitonin is one of the precursor proteins of calcitonin, its levels are elevated in bacterial infection, and it has been established as a diagnostic marker for severe bacterial infections. Objective: This study evaluated the clinical usefulness of procalcitonin for predicting disease severity and prognosis of cellulitis. Methods: We reviewed the medical records of 160 patients diagnosed with cellulitis in the past 3 years. Body temperature, procalcitonin, white blood cell (WBC), erythrocyte sedimentation rate (ESR), and C-reactive protein (CRP) levels were measured on their first day of admission. The associations of procalcitonin, WBC, ESR, and CRP with the body temperature and the number of hospitalized days were assessed. Results: Procalcitonin, WBC, and CRP showed a positive correlation with body temperature. In addition, procalcitonin, WBC, ESR, and CRP showed a positive correlation with number of hospitalized days (p＜0.05). Conclusion: In patients diagnosed with cellulitis, proclacitonin was a helpful parameter to indicate the severity of disease and also a useful predictor of prognosis.
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참고문헌 (22)
참고문헌 신청
van Rossum AM. / 2004 / Procalcitonin as an early marker of infection in neonates and children / Lancet Infect Dis 4:620~630
Russwurm S. / 1999 / Molecular aspects and natural source of procalcitonin / Clin Chem Lab Med 37:789~797
Müller B. / 2001 / Ubiquitous expression of the calcitonin-i gene in multiple tissues in response to sepsis / J Clin Endocrinol Metab 86:396~404
Schuetz P. / 2010 / Procalcitonin for guidance of antibiotic therapy / Expert Rev Anti Infect Ther 8:575~587
Kim SI. / 2000 / Clinical usefulness of procalcitonin in febrile Patients;comparison with erythrocyte sedimentation rate and C-reactive protein / Korean J Infect Dis 32:129~134
Russwurm S. / 1999 / Molecular aspects and natural source of procalcitonin / Clin Chem Lab Med 37:789~797
Müller B. / 2001 / Ubiquitous expression of the calcitonin-i gene in multiple tissues in response to sepsis / J Clin Endocrinol Metab 86:396~404
Schuetz P. / 2010 / Procalcitonin for guidance of antibiotic therapy / Expert Rev Anti Infect Ther 8:575~587
Kim SI. / 2000 / Clinical usefulness of procalcitonin in febrile Patients;comparison with erythrocyte sedimentation rate and C-reactive protein / Korean J Infect Dis 32:129~134
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