지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.12
- 수록면
- 51 - 57 (7page)
- DOI
- https://doi.org/10.22470/pemj.2017.00101
이용수
초록· 키워드
오류제보하기
Purpose
To investigate the predictors of perforated appendicitis (PA) in pediatric patients with appendicitis seen in the emergency department.
Methods
We retrospectively reviewed 564 pediatric patients (< 16 years) who visited the emergency department and subsequently had pathologically confirmed appendicitis from 2005 through 2014. Clinical features, inflammatory markers, including the white blood cell (WBC), neutrophil, and lymphocyte counts, neutrophil-to-lymphocyte ratio, C-reactive protein (CRP) concentration, erythrocyte sedimentation rate (ESR), and the Alvarado score were compared between the patients with and without PA regarding their predictability of PA.
Results
Of 564 pediatric patients with appendicitis, 204 (36.2%) had PAs. The patients with PA had longer duration of symptoms and median length of hospital stay, more frequent nausea and vomiting, and higher median WBC and neutrophil counts, neutrophil-to-lymphocyte ratio, ESR, and CRP concentration. Overall, WBC count showed the highest sensitivity of 79.9% and negative predictive value of 82.6%, and CRP concentration had the highest area under the receiver operating characteristic curve of 0.72. Multivariable logistic analysis showed that WBC count > 13.5 × 109/L (odds ratio [OR], 3.27; confidence interval [CI], 1.49-7.18; P = 0.003) and ESR > 15 mm/h (OR, 3.18; 95% CI, 2.13-4.74; P < 0.001) are independent predictors of PA.
Conclusion
WBC count and ESR might be better predictors of PA in pediatric patients with appendicitis in the emergency department than the Alvarado score and CRP concentration.
목차
등록된 정보가 없습니다.
참고문헌 (24)
참고문헌 신청
Gamal R / 1990 / Appendicitis in children aged 13years and younger / Am J Surg 159:589~592
Rappaport WD / 1989 / Factors responsible for the high perforation rate seen in early childhood appendicitis / Am Surg 55:602~605
Korner H / 1997 / Incidence of acute nonperforated and perforated appendicitis: age-specific and sex-specific analysis / World J Surg 21:313~317
Rothrock SG / 2000 / Acute appendicitis in children:emergency department diagnosis and management / Ann Emerg Med 36:39~51
Chang YJ / 2010 / Misdiagnosed acute appendicitis in children in the emergency department / Chang Gung Med J 33:551~557
Rappaport WD / 1989 / Factors responsible for the high perforation rate seen in early childhood appendicitis / Am Surg 55:602~605
Korner H / 1997 / Incidence of acute nonperforated and perforated appendicitis: age-specific and sex-specific analysis / World J Surg 21:313~317
Rothrock SG / 2000 / Acute appendicitis in children:emergency department diagnosis and management / Ann Emerg Med 36:39~51
Chang YJ / 2010 / Misdiagnosed acute appendicitis in children in the emergency department / Chang Gung Med J 33:551~557
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