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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2019.1
- 수록면
- 482 - 489 (8page)
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초록· 키워드
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Reproductive biotechnology has developed rapidly and is now able to overcome many birth difficulties due to infertility or the transmission of genetic diseases. Here we introduce the next generation of assisted reproductive technologies (ART), such as mitochondrial replacement technique (MRT) or genetic correction in eggs with micromanipulation. Further, we suggest that the transmission of genetic information from somatic cells to subsequent generations without gametes should be useful for people who suffer from infertility or genetic diseases. Pluripotent stem cells (PSCs) can be converted into germ cells such as sperm or oocytes in the laboratory. Notably, germ cells derived from nuclear transfer embryonic stem cells (NT-ESCs) or induced pluripotent stem cells (iPSCs) inherit the full parental genome. The most important issue in this technique is the generation of a haploid chromosome from diploid somatic cells. We hereby examine current science and limitations underpinning these important developments and provide recommendations for moving forward.
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등록된 정보가 없습니다.
참고문헌 (80)
참고문헌 신청
Sherrod RA / 2004 / Understanding the emotional aspects of infertility : Implications for nursing practice / J Psychosoc Nurs Ment Health Serv 42:40~47
Boulet SL / 2015 / Trends in use of and reproductive outcomes associated with intracytoplasmic sperm injection / JAMA 313:255~263
Verhaak CM / 2007 / Women's emotional adjustment to IVF : A systematic review of 25 years of research / Hum Reprod Update 13:27~36
Maleki-Saghooni N / 2017 / Effectiveness of infertility counseling on pregnancy rate in infertile patients undergoing assisted reproductive technologies: A systematic review and meta-analysis / Int J Reprod Biomed (Yazd) 15:391~402
Edwards RG / 1980 / Establishing full-term human pregnancies using cleaving embryos grown in vitro / Br J Obstet Gynaecol 87:737~756
Boulet SL / 2015 / Trends in use of and reproductive outcomes associated with intracytoplasmic sperm injection / JAMA 313:255~263
Verhaak CM / 2007 / Women's emotional adjustment to IVF : A systematic review of 25 years of research / Hum Reprod Update 13:27~36
Maleki-Saghooni N / 2017 / Effectiveness of infertility counseling on pregnancy rate in infertile patients undergoing assisted reproductive technologies: A systematic review and meta-analysis / Int J Reprod Biomed (Yazd) 15:391~402
Edwards RG / 1980 / Establishing full-term human pregnancies using cleaving embryos grown in vitro / Br J Obstet Gynaecol 87:737~756
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