지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
오류제보하기
Objectives: Although vaginal estrogen is highly effective in alleviating genitourinary symptoms of menopause (GSM), some women are reluctant to use hormonal treatment. Our aim was to evaluate the effect of a zinc-containing vaginal moisturizer gel on GSM. Methods: Women with GSM were enrolled. Patients were asked to use the vaginal gel daily for 2 weeks. Vaginal Health Index (VHI) was calculated. Visual analogue scale (VAS) was obtained on vaginal pain, dryness, burning, itching, dyspareunia and dysuria before and 2 weeks after the completion of treatment. Vaginal cytology was obtained. Vulvovaginal symptom questionnaire (VSQ- 21) was used to assess subjective symptoms. Results: Thirty-seven women with GSM participated in the study. The VHI improved significantly (mean ± standard deviation, 13 ± 4 before vs. 17 ± 4 after treatment, P < 0.01). The patient reported VAS combined score was significantly lower after the treatment (18 ± 14 before vs. 7 ± 12 after treatment, P < 0.01). The largest improvement occurred in vaginal dryness. The maturation value did not change significantly. There were no signs of inflammation on vaginal cytology. VSQ-21 combined scores also improved significantly (7.9 ± 5.5 before vs. 2.7 ± 3.6 after the intervention, P < 0.01). Side effects were rare and minor. Conclusions: Novel zinc-containing vaginal moisturizer gel significantly improves postmenopausal vulvovaginal symptoms without serious side effects.
목차
등록된 정보가 없습니다.
참고문헌 (19)
참고문헌 신청
Weber MA / 2015 / Assessment of vaginal atrophy : a review / Int Urogynecol J 26:15~28
Bachmann GA / 2000 / Diagnosis and treatment of atrophic vaginitis / Am Fam Physician 61:3090~3096
Levine KB / 2008 / Vulvovaginal atrophy is strongly associated with female sexual dysfunction among sexually active postmenopausal women / Menopause 15:661~666
Nappi RE / 2010 / Women’s voices in the menopause : results from an international survey on vaginal atrophy / Maturitas 67:233~238
Fatemeh Shobeiri / 2016 / Quality of Life in Postmenopausal Women in Iran: A Population-based Study / 대한폐경학회지 22(1):31~38
Bachmann GA / 2000 / Diagnosis and treatment of atrophic vaginitis / Am Fam Physician 61:3090~3096
Levine KB / 2008 / Vulvovaginal atrophy is strongly associated with female sexual dysfunction among sexually active postmenopausal women / Menopause 15:661~666
Nappi RE / 2010 / Women’s voices in the menopause : results from an international survey on vaginal atrophy / Maturitas 67:233~238
Fatemeh Shobeiri / 2016 / Quality of Life in Postmenopausal Women in Iran: A Population-based Study / 대한폐경학회지 22(1):31~38
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