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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2019.1
- 수록면
- 1,400 - 1,410 (11page)
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초록· 키워드
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Purpose The aim of this study was to investigate epidemiology, clinical characteristics and sex differences of patients with lung cancer using nationwide registry in Korea. Materials and Methods The Korean Association for Lung Cancer developed a registry in cooperation with the Korean Central Cancer Registry, and surveyed about 10% of lung cancer cases. For this first survey of cases diagnosed in 2014, cases were selected through a systematic sampling method. Results Total 2,621 lung cancer patients were surveyed, and the median patient age was 70 years. During the study period, adenocarcinoma was the most frequent histologic type, the proportion of female patients was 28.4%, and women had a better prognosis (median survival, not reached vs. 13 months; p < 0.001) than did men for non-small cell lung cancer. The proportion of never-smokers was 36.4%, and never-smoking was more prevalent in women than in men (87.5 vs. 16.0%, p < 0.001). Epidermal growth factor receptor (EGFR) mutations were found in 36.8% of stage IV adenocarcinoma patients, and higher in female compared to male patients (51.2 vs. 26.6%, p < 0.001). In addition, patients with EGFR mutation showed better survival (median survival, 18 months vs. 8 months; p < 0.001) than patients without EGFR mutation in these patients. Conclusion This is the first survey to gather unbiased nationwide lung cancer statistics in Korea. More than one-third of lung cancer patients had no smoking history. Female had a high proportion of non-smoker, more adenocarcinoma with EGFR mutation and generally better prognosis than male.
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참고문헌 (30)
참고문헌 신청
정규원 / 2018 / Cancer Statistics in Korea: Incidence, Mortality, Survival, and Prevalence in 2015 / Cancer Research and Treatment 50(2):303~316
Cho J / 2017 / Proportion and clinical features of never-smokers with non-small cell lung cancer / Chin J Cancer 36:20
Wakelee HA / 2007 / Lung cancer incidence in never smokers / J Clin Oncol 25:472~478
Yatabe Y / 2015 / EGFR mutation testing practices within the Asia Pacific region : results of a multicenter diagnostic survey / J Thorac Oncol 10:438~445
Lee C / 2000 / Characteristics of lung cancer in Korea, 1997 / Lung Cancer 30:15~22
Cho J / 2017 / Proportion and clinical features of never-smokers with non-small cell lung cancer / Chin J Cancer 36:20
Wakelee HA / 2007 / Lung cancer incidence in never smokers / J Clin Oncol 25:472~478
Yatabe Y / 2015 / EGFR mutation testing practices within the Asia Pacific region : results of a multicenter diagnostic survey / J Thorac Oncol 10:438~445
Lee C / 2000 / Characteristics of lung cancer in Korea, 1997 / Lung Cancer 30:15~22
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