개인구독
소속 기관이 없으신 경우, 개인 정기구독을 하시면 저렴하게
논문을 무제한 열람 이용할 수 있어요.
지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
이용수
초록· 키워드
오류제보하기
Objectives: The purpose of this study was to investigate the association between fracture risk and proton pump inhibitor (PPI) use to establish evidence for defining high-risk groups of fracture among PPI users. Methods: A case-control study was performed using the National Health Insurance Sample Cohort Database from January 2002 to December 2013. The cases included all incidences of major fractures identified from January 2011 to December 2013, and up to four controls were matched to each case by age, gender, osteoporosis, and Charlson comorbidity index. Conditional logistic regression was used to calculate the adjusted odds ratio (aOR) and associated 95% confidence interval (CI). Results: Overall, 14,295 cases were identified, and 63,435 controls were matched to the cases. The aOR of fractures related to the use of PPIs was 1.06 (95% CI: 1.01-1.11). There was a statistically significant association between fracture and PPI use within 3 months of the last dose, and a trend of increasing fracture risk with increasing cumulative PPI dose. The risk of fracture was significantly higher in patients who took PPIs for more than 1 year during the 2-year observation period. Conclusion: Patients who have been using PPIs for more than 1 year should be warned about the risk of fracture during or at least 3 months after discontinuing the PPI.
목차
등록된 정보가 없습니다.
참고문헌 (17)
참고문헌 신청
van Pinxteren B / 2010 / Shortterm treatment with proton pump inhibitors, H2-receptor antagonists and prokinetics for gastro-oesophageal reflux disease-like symptoms and endoscopy negative reflux disease / Cochrane Database Syst Rev (11):CD002095
Malfertheiner P / 2017 / Proton-pump inhibitors:understanding the complications and risks / Nat Rev Gastroenterol Hepatol 14(12):697~710
김종주 / 2018 / 국민건강보험 12년 표본코호트자료에 근거한 국내 프로톤펌프저해제 사용 현황 / 약 학 회 지 62(3):171~178
Health Insurance Review and Assessment Service: Healthcare Bigdata Hub / Statistics
Bhatt DL / 2008 / ACCF/ACG/AHA 2008expert consensus document on reducing the gastrointestinal risks of antiplatelet therapy and NSAID use: a report of the American College of Cardiology Foundation Task Force on Clinical Expert Consensus Documents / Circulation 118:1894~1909
Malfertheiner P / 2017 / Proton-pump inhibitors:understanding the complications and risks / Nat Rev Gastroenterol Hepatol 14(12):697~710
김종주 / 2018 / 국민건강보험 12년 표본코호트자료에 근거한 국내 프로톤펌프저해제 사용 현황 / 약 학 회 지 62(3):171~178
Health Insurance Review and Assessment Service: Healthcare Bigdata Hub / Statistics
Bhatt DL / 2008 / ACCF/ACG/AHA 2008expert consensus document on reducing the gastrointestinal risks of antiplatelet therapy and NSAID use: a report of the American College of Cardiology Foundation Task Force on Clinical Expert Consensus Documents / Circulation 118:1894~1909
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Proton-pump Inhibitor Use and Fracture Risk: An Updated Systematic Review and Meta-analysis
대한골대사학회지
2018 .01
-
Big Data Statistical Analysis of Facial Fractures in Korea
Journal of Korean Medical Science
2020 .01
-
Second hip fracture in Hong Kong – Incidence, demographics, and mortality
Osteoporosis and Sarcopenia
2020 .01
-
Fracture patterns and causes in the craniofacial region: an 8-year review of 2076 patients
Maxillofacial Plastic Reconstructive Surgery
2018 .10
-
노인에서 골절에 대한 우울증의 영향: 후향적 코호트 연구
Korean Journal of Family Practice
2019 .06
-
Fracture Experiences and Long-Term Care Initiation among Older Population: Analysis of Korean National Health Insurance Service-Senior Cohort Study
Annals of geriatric medicine and research
2019 .01
-
Population-based Analysis for Risk of Suicide Death in Elderly Patients after Osteoporotic Fracture: a Nested Case-Control Study
Journal of Korean Medical Science
2021 .09
-
Association of Body Mass Index and Fracture Risk Varied by Affected Bones in Patients with Diabetes: A Nationwide Cohort Study
Diabetes and Metabolism Journal
2023 .03
-
Is ankle fracture related to low bone mineral density and subsequent fracture? A systematic review
Osteoporosis and Sarcopenia
2020 .01
-
Clinical Characteristics of Primary and Secondary Osteoporotic Fractures: Data from Single Referral Center Emergency Department
대한골대사학회지
2019 .01
-
Analysis of Fracture Patterns and Characteristics in Sacral Insufficiency Fracture: Do Sacral Fractures Occur in Patients Who Had Previous Lumbosacral Fusion Insufficiency Fractures or Stress Fractures?
Asian Spine Journal
2021 .12
-
Association of Alcohol Intake and Fracture Risk in Elderly Varied by Affected Bones: A Nationwide Longitudinal Study
PSYCHIATRY INVESTIGATION
2020 .01
-
Individualized fracture risk assessment: State-of-the-art and room for improvement
Osteoporosis and Sarcopenia
2018 .01
-
고령의 골다공증이 있는 고관절 골절 환자에서 골주사 검사를 이용한 간과된 동반 골절에 대한 분석
대한골절학회지
2024 .07
-
Statin Therapy and the Risk of Osteoporotic Fractures in Patients with Metabolic Syndrome: a Nested Case-Control Study
지질·동맥경화학회지
2021 .09
-
Effect of Osteoporosis Medication on Fracture Healing: An Evidence Based Review
대한골대사학회지
2020 .01
-
The Epidemiology of Fracture in Patients with Acute Ischemic Stroke in Korea
Journal of Korean Medical Science
2019 .01
-
Risk factors and epidemiological profile of hip fractures in Indian population: A case-control study
Osteoporosis and Sarcopenia
2017 .01
-
Effect of Dipeptidyl Peptidase-4 Inhibitors on the Risk of Bone Fractures in a Korean Population
Journal of Korean Medical Science
2019 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0