지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 한국미생물생명공학회 Journal of Microbiology and Biotechnology Journal of Microbiology and Biotechnology 제30권 제1호
- 발행연도
- 2020.1
- 수록면
- 71 - 78 (8page)
이용수
초록· 키워드
오류제보하기
Lactobacillus sakei S1 strongly inhibits the expression of interleukin (IL)-6 and IL-1β in lipopolysaccharide-induced peritoneal macrophages by a mechanism for which lactic acid bacteria from kimchi that inhibit tumor necrosis factor-alpha (TNF-α) were isolated. Therefore, we further evaluated the protective effect of this strain on the colitis mouse model induced by 2,4,6-trinitrobenzene sulfonic acid (TNBS). TNBS significantly elevated myeloperoxidase (MPO) expression, macroscopic scores, and colon shortening. Oral L. sakei S1 administration resulted in reduction of TNBS-induced loss in body weight, colon shortening, MPO activity, expression of cyclooxygenase (COX)-2, inducible nitric oxide synthase (iNOS) and nuclear factor-kappa B (NF-κB). L. sakei S1 inhibited the expression of inflammatory cytokines IL-1β, IL-6 and TNF-α, induced by TNBS, but enhanced IL-10 expression. L. sakei S1 showed resistance to artificial digestive juices and adherence to intestinal epithelial Caco-2 cells. Thus, L. sakei S1 may inhibit the NF-κB pathway and be used in functional food to treat colitis.
목차
등록된 정보가 없습니다.
참고문헌 (31)
참고문헌 신청
Neuman MG / 2012 / Inflammatory bowel disease : role of diet, microbiota, life style / Trans. Res 160:29~44
Shanahan F / 2002 / Gut flora in gastrointestinal disease / Eur. J. Surg. Suppl 587:47~52
Jang SE / 2014 / Lactobacillus plantarum CLP-0611 ameliorates colitis in mice by polarizing M1 to M2-like macrophages / Int. Immunopharmacol 21:186~192
Chandran P / 2003 / Inflammatory bowel disease : dysfunction of GALT and gut bacterial flora(I) / Surgeon 1:63~75
Aderem A / 2000 / Toll-like receptors in the induction of the innate immune response / Nature 406:782~787
Shanahan F / 2002 / Gut flora in gastrointestinal disease / Eur. J. Surg. Suppl 587:47~52
Jang SE / 2014 / Lactobacillus plantarum CLP-0611 ameliorates colitis in mice by polarizing M1 to M2-like macrophages / Int. Immunopharmacol 21:186~192
Chandran P / 2003 / Inflammatory bowel disease : dysfunction of GALT and gut bacterial flora(I) / Surgeon 1:63~75
Aderem A / 2000 / Toll-like receptors in the induction of the innate immune response / Nature 406:782~787
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Lactobacillus plantarum C29 Alleviates TNBS-Induced Memory Impairment in Mice
Journal of Microbiology and Biotechnology
2018 .01
-
Mass-Based Metabolomic Analysis of Lactobacillus sakei and Its Growth Media at Different Growth Phases
Journal of Microbiology and Biotechnology
2017 .01
-
Characterization and Immunomodulation Activity of Lactobacillus sakei L2 and L8 Isolated from Chicken Cecum
한국미생물·생명공학회지
2016 .01
-
Latilactobacillus sakei WIKIM31 Decelerates Weight Gain in High-Fat Diet-Induced Obese Mice by Modulating Lipid Metabolism and Suppressing Inflammation
Journal of Microbiology and Biotechnology
2021 .11
-
Immunostimulatory effect of heat inactivated Lactobacillus sakei and derived nanosized bacterial particles on RAW 264.7 cells
미생물학회지
2023 .06
-
Semi-Rational Screening of Probiotics from the Fecal Flora of Healthy Adults against DSS-Induced Colitis Mice by Enhancing Anti-Inflammatory Activity and Modulating the Gut Microbiota
Journal of Microbiology and Biotechnology
2019 .01
-
Effect of saccharin on inflammation in 3T3-L1 adipocytes and the related mechanism
Nutrition Research and Practice
2020 .04
-
Effect of saccharin on inflammation in 3T3-L1 adipocytes and the related mechanism
Nutrition Research and Practice
2020 .04
-
A Double-Blind, Placebo Controlled-Trial of a Probiotic Strain Lactobacillus sakei Probio-65 for the Prevention of Canine Atopic Dermatitis
Journal of Microbiology and Biotechnology
2015 .01
-
Heat-Treated Paraprobiotic Latilactobacillus sakei KU15041 and Latilactobacillus curvatus KU15003 Show an Antioxidant and Immunostimulatory Effect
Journal of Microbiology and Biotechnology
2024 .02
-
Effects of natural raw meal (NRM) on high-fat diet and dextran sulfate sodium (DSS)-induced ulcerative colitis in C57BL/6J mice
Nutrition Research and Practice
2015 .12
-
Effects of natural raw meal (NRM) on high-fat diet and dextran sulfate sodium (DSS)-induced ulcerative colitis in C57BL/6J mice
Nutrition Research and Practice
2015 .12
-
Inhibition of TNFα-induced interleukin-6 gene expression by barley (Hordeum vulgare) ethanol extract in BV-2 microglia
Genes & Genomics
2019 .01
-
CRISPR/Cas systems and anti-repeat sequences of Lactobacillus curvatus, Lactobacillus graminis, Lactobacillus fuchuensis, and Lactobacillus sakei genomes
미생물학회지
2021 .03
-
Lipoteichoic Acid of Lactobacillus plantarum Inhibits Poly I:C-induced IL-8 Production in Porcine Intestinal Epithelial Cells
한국미생물학회 학술대회논문집
2017 .04
-
항균활성 김치유산균의 분리 및 그 특성 규명
한국생활과학회지
2017 .12
-
Paeoniflorin ameliorates Aβ-stimulated neuroinflammation via regulation of NF-κB signaling pathway and Aβ degradation in C6 glial cells
Nutrition Research and Practice
2020 .12
-
Paeoniflorin ameliorates Aβ-stimulated neuroinflammation via regulation of NF-κB signaling pathway and Aβ degradation in C6 glial cells
Nutrition Research and Practice
2020 .12
-
Cigarette Smoke Extract Enhances IL-17A-Induced IL-8 Production via Up-Regulation of IL-17R in Human Bronchial Epithelial Cells
Molecules and Cells
2018 .03
이 논문의 저자 정보
최근 본 자료
댓글(0)
0