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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2020.1
- 수록면
- 7 - 19 (13page)
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초록· 키워드
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The current goal of inflammatory bowel disease (IBD) treatment is a symptom-free everyday life accompanied by mucosal healing with minimal use of corticosteroids. Recent therapeutic advances, particularly, the emergence of anti-tumor necrosis factor (anti-TNF) antibodies, have changed the natural history of IBD. Additionally, these advances also led to the emergence of the therapeutic concept of the “treat to target” strategy. With the development of new drugs and clinical trials, not only biologics but also small molecules have been applied to clinical practice to better individualize and optimize therapy. However, if newer drugs, including anti-TNF therapies, are recommended for all patients diagnosed with IBD, a significant number of patients will be overtreated. The basic goal of IBD treatment is still to make the best use of conventional treatments based on IBD pathophysiology. Thus, physicians should be familiar with the modes of action of the available drugs. In this review, the author discusses the existing data for many approved drugs and provide insights for optimizing current treatments for the management of patients with IBD in the era of biologics.
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참고문헌 (77)
참고문헌 신청
Nakase H / 2015 / How to select and use IBD drugs / Yodosha Co., Ltd.
Nakase H / 2018 / To master the optimal therapy for ulcerative colitis / Igakutokangosha Co., Ltd
Stolfi C / 2013 / Mechanisms of action of non-steroidal anti-inflammatory drugs(NSAIDs)and mesalazine in the chemoprevention of colorectal cancer / Int J Mol Sci 14:17972~17985
Oh-Oka K / 2017 / Induction of colonic regulatory T cells by mesalamine by activating the aryl hydrocarbon receptor / Cell Mol Gastroenterol Hepatol 4:135~151
Marshall JK / 1995 / Rectal aminosalicylate therapy for distal ulcerative colitis : a meta-analysis / Aliment Pharmacol Ther 9:293~300
Nakase H / 2018 / To master the optimal therapy for ulcerative colitis / Igakutokangosha Co., Ltd
Stolfi C / 2013 / Mechanisms of action of non-steroidal anti-inflammatory drugs(NSAIDs)and mesalazine in the chemoprevention of colorectal cancer / Int J Mol Sci 14:17972~17985
Oh-Oka K / 2017 / Induction of colonic regulatory T cells by mesalamine by activating the aryl hydrocarbon receptor / Cell Mol Gastroenterol Hepatol 4:135~151
Marshall JK / 1995 / Rectal aminosalicylate therapy for distal ulcerative colitis : a meta-analysis / Aliment Pharmacol Ther 9:293~300
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