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- 자료유형
- 학술대회자료
- 저자정보
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- 대한약학회 대한약학회 학술대회 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2-2
- 발행연도
- 2003.1
- 수록면
- 781 - 781 (1page)
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Sauchinone, a known lignan, was isolated from the root of Saururus chinensis as an active principle responsible for inhibiting the production of NO in LPS-stimulated RAW264.7 cells by activity-guided fractionation. Sauchinone dose-dependently inhibited not only the production of NO, but also the expression of iNOS mRNA and protein in LPS-stimulated RAW 264.7 cells. Furthermore, sauchinone prevented LPS-induced NF-kB activation, which is known to play a critical role in iNOS expression, assessed by a reporter assay under the control of NF-kB. (omitted)
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Sauchinone inhibits iNOS, TNF-$\alpha$ and COX-2 induction by LPS
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Sauchinone, a Lignan from Saururus chinensis, Inhibits Staurosporine-induced Apoptosis in C6 Rat Glioma Cells
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Suppression of RelA/p65 Transactivation Activity by a Lignoid Manassantin isolated from Saururus chinensis
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Protective effects of 1-epi-sauchinone against ethanol-induced gastric injury in rats
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