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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
오류제보하기
p11 protein (S100A10) is downregulated in depressive-like states of human and rodent. Antidepressant drug treatment increases p11 levels in rodent models. We reviewed studies demonstrating that p11 levels are regulated in depression and by antidepressant treatment and that p11 upregulation exerts antidepressant effects. Current studies on p11 underscore the importance of p11 as a potential antidepressant target.
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등록된 정보가 없습니다.
참고문헌 (31)
참고문헌 신청
Rescher U / 2008 / S100A10/p11: family, friends and functions / Pflugers Arch 455:575~582
Svenningsson P / 2007 / p11 (S100A10)--an inducible adaptor protein that modulates neuronal functions / Curr Opin Pharmacol 7:27~32
Svenningsson P / 2006 / Alterations in 5-HT1B receptor function by p11 in depression-like states / Science 311:77~80
Alexander B / 2010 / Reversal of depressed behaviors in mice by p11 gene therapy in the nucleus accumbens / Sci Transl Med 2:54~76
Warner-Schmidt JL / 2010 / A role for p11 in the antidepressant action of brain-derived neurotrophic factor / Biol Psychiatry 68:528~535
Svenningsson P / 2007 / p11 (S100A10)--an inducible adaptor protein that modulates neuronal functions / Curr Opin Pharmacol 7:27~32
Svenningsson P / 2006 / Alterations in 5-HT1B receptor function by p11 in depression-like states / Science 311:77~80
Alexander B / 2010 / Reversal of depressed behaviors in mice by p11 gene therapy in the nucleus accumbens / Sci Transl Med 2:54~76
Warner-Schmidt JL / 2010 / A role for p11 in the antidepressant action of brain-derived neurotrophic factor / Biol Psychiatry 68:528~535
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