지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 한국응용생명화학회 Journal of applied biological chemistry Journal of applied biological chemistry 제53권 제5호
- 발행연도
- 2010.1
- 수록면
- 570 - 577 (8page)
이용수
초록· 키워드
오류제보하기
Dietary fiber (DF) and resistant starch (RS) in the grains of cereals are fermented into short chain fatty acids (SCFA), including butyrate, propionate, and acetate, in the large intestine, and are absorbed into the blood. Effectiveness of SCFA in reducing myocardial damage was evaluated in a rat model of 30 min ischemia and 3 h reperfusion with administration of SCFA (10 mg/kg) by peritoneal injection 1 h before occlusion. Butyrate and propionate significantly attenuated infarct size, an indicator of myocardial damage, when assessed by 2,3,5-triphenyltetrazolium chloride staining, reduced apoptosis in terminal deoxynucleotidyl transferase-mediated dUTP nick-end labeling staining, and increased Bcl-2/Bax ratio, a determinant of cell survival in the apoptotic pathway. In addition, butyrate significantly attenuated the level of caspase-3, an executioner caspase, in an immunohistochemical assay. These results demonstrate that butyrate and propionate, produced by fermentation of DF and RS in the large intestine, could prevent myocardial infarction by attenuating apoptosis, possibly through inhibition of histone deacetylases. Thus, varieties of cereals or diets that produce a large amount of butyrate and propionate by fermentation could be beneficial in reducing myocardial infarction.
목차
등록된 정보가 없습니다.
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Butyrate and Propionate, Short Chain Fatty Acids, Attenuate Myocardial Damages by Inhibition of Apoptosis in a Rat Model of Ischemia-reperfusion
Applied Biological Chemistry
2010 .01
-
Apple Pectin, a Dietary Fiber, Ameliorates Myocardial Injury by Inhibiting Apoptosis in a Rat Model of Ischemia-reperfusion
한국식품영양과학회 학술대회발표집
2013 .11
-
Xyloglucan, a Dietary Fiber, Ameliorates Myocardial Injury by Inhibiting Apoptosis in a Rat Model of Ischemia-Reperfusion
한국식품영양과학회 학술대회발표집
2014 .10
-
Methanol Extract of Cassia mimosoides var. nomame Attenuates Myocardial Injury by Inhibition of Apoptosis in a Rat Model of Ischemia-Reperfusion
Preventive Nutrition and Food Science
2012 .09
-
호르몬과 단쇄지방산이 HepG2 Cell 내에서 CYP7A1발현에 미치는 효과
한국식품영양과학회지
2005 .06
-
Protective Effects of Arabinogalactan-Peptide Isolated from Wheat Flour against Myocardial Injury in an Ischemia/Reperfusion Rat Model
Preventive Nutrition and Food Science
2018 .12
-
Methanol Extract of Peony Root (Peonia lactiflora) and its Ethyl Acetate Fraction Attenuate Heart and Brain Injury in a Rat Model of Ischemia-Reperfusion
Applied Biological Chemistry
2011 .01
-
Testosterone Propionate의 投與가 어린 숫흰쥐의 副腎에 미치는 影響
Korean Journal of Agricultural Science
1976 .12
-
쪽(Polygonum tinctortium) 세포의 형질전환 및 쪽 세포에서 Sodium Butyrate가 Green Fluorescent Protein 발현에 미치는 영향
Applied Biological Chemistry
2001 .01
-
Butyrate and taurine exert a mitigating effect on the inflamed distal intestine of European sea bass fed with a high percentage of soybean meal
Fisheries and Aquatic Sciences
2016 .01
-
Dietary Fiber의 면역조절기능과 Short Chain Acid에 관한 연구
식품기술
2002 .01
-
빵의 프로피온산 함량 분석방법 개선
한국식품위생안전성학회지
2009 .01
-
Methanol Extract of Cassia mimosoides var. nomame and Its Ethyl Acetate Fraction Attenuate Brain Damage by Inhibition of Apoptosis in a Rat Model of Ischemia-Reperfusion
Journal of Food Science and Nutrition
2010 .12
-
Abundance of Fecal Butyrate-producing Bacteria and Inflammatory Markers in Ulcerative Colitis Patients: A Comparative Study
한국식품영양과학회 학술대회발표집
2016 .10
-
下垂体剔出 숫흰쥐에 있어서 Testosterone Propionate의 投與가 副賢에 미치는 影響
Korean Journal of Agricultural Science
1974 .12
-
바나나 껍질과 파인애플 껍질 Ester Synthetase를 이용한 Ethyl Butyrate의 효소적 합성
한국식품영양과학회지
2017 .09
이 논문의 저자 정보
최근 본 자료
댓글(0)
0