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논문 기본 정보
- 자료유형
- 학술대회자료
- 저자정보
- 발행연도
- 2021.7
- 수록면
- 217 - 217 (1page)
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초록· 키워드
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Nonalcoholic fatty liver disease (NAFLD) is a liver disease syndrome that appears in people without a history of drinking. It causes various lesions ranging from overweight or obesity to simple fatty liver, steatohepatitis, fatty liver fibrosis, and cirrhosis. Nonalcoholic fatty liver disease can progress from simple fatty liver to non-alcoholic steatohepatitis (NASH) to liver fibrosis, and in 5-15% of patients, liver cirrhosis, hepatocellular carcinoma (HCC) or end-stage liver disease, such as liver failure. There are differences in the phenotype and formation mechanism of the fatty liver animal model produced according to the method. Selecting the most suitable animal model according to the study goals and taking into account factors such as complications of this NAFLD model do not affect the use of the animal model. It is recommended to select an experimental model that is as similar to human NAFLD as possible, has a simple method, has a high success rate, has a low animal mortality rate, has a short production cycle, and has good redundancy. 1. Dietary Induction Model It has been reported that a methionine-choline-deficie ... 전체 초록 보기
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