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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2020.10
- 수록면
- 299 - 307 (9page)
- DOI
- https://doi.org/10.3904/kjm.2020.95.5.299
이용수
초록· 키워드
오류제보하기
Nonalcoholic fatty liver disease (NAFLD) is the most common liver disease worldwide, and is characterized by fat accumulation at levels exceeding 5% in hepatocytes due to insulin resistance. The disease spectrum ranges from simple nonalcoholic fatty liver (NAFL) to nonalcoholic steatohepatitis (NASH)/NASH-related fibrosis or cirrhosis defined by histological findings. Unlike simple NAFL, NASH/NASH-related fibrosis or cirrhosis increases the risk of liver-related morbidity or mortality. Therefore, accurate diagnosis of NASH/NASH-related fibrosis or cirrhosis is needed for management of patients with these diseases. Currently, liver biopsy is the only way to confirm the presence of NASH in an individual with features of NAFLD, but this has some limitations, including sample error, interpretation error, and the invasiveness of the procedure. Therefore, there have been a number of attempts to develop noninvasive methods for differential diagnosis of NASH/NASH-related fibrosis or cirrhosis easily and quickly. Here, we review the assessments for diagnosing NAFLD and the methods for differential diagnosis of NASH/NASH-related fibrosis or cirrhosis.
목차
등록된 정보가 없습니다.
참고문헌 (48)
참고문헌 신청
Chalasani N / 2018 / The diagnosis and management of nonalcoholic fatty liver disease : practice guidance from the American Association for the Study of Liver Diseases / Hepatology 67:328~357
De Minicis S / 2013 / From NAFLD to NASH and HCC : pathogenetic mechanisms and therapeutic insights / Curr Pharm Des 19:5239~5249
Lee JY / 2007 / Prevalence and risk factors of non-alcoholic fatty liver disease in potential living liver donors in Korea : a review of 589 consecutive liver biopsies in a single center / J Hepatol 47:239~244
Williams CD / 2011 / Prevalence of nonalcoholic fatty liver disease and nonalcoholic steatohepatitis among a largely middle-aged population utilizing ultrasound and liver biopsy : a prospective study / Gastroenterology 140:124~131
Speliotes EK / 2010 / Fatty liver is associated with dyslipidemia and dysglycemia independent of visceral fat : the Framingham Heart Study / Hepatology 51:1979~1987
De Minicis S / 2013 / From NAFLD to NASH and HCC : pathogenetic mechanisms and therapeutic insights / Curr Pharm Des 19:5239~5249
Lee JY / 2007 / Prevalence and risk factors of non-alcoholic fatty liver disease in potential living liver donors in Korea : a review of 589 consecutive liver biopsies in a single center / J Hepatol 47:239~244
Williams CD / 2011 / Prevalence of nonalcoholic fatty liver disease and nonalcoholic steatohepatitis among a largely middle-aged population utilizing ultrasound and liver biopsy : a prospective study / Gastroenterology 140:124~131
Speliotes EK / 2010 / Fatty liver is associated with dyslipidemia and dysglycemia independent of visceral fat : the Framingham Heart Study / Hepatology 51:1979~1987
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