지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2020.1
- 수록면
- 80 - 92 (13page)
이용수
초록· 키워드
오류제보하기
Purpose: The purpose of this study was to evaluate the prognostic value of skeletal muscle depletion measured on computed tomography (CT) in patients with non-metastatic invasive breast cancer. Methods: This retrospective study included 577 consecutive women (mean age ± standard deviation: 48.9 ± 10.2 years with breast cancer who underwent a preoperative positronemission tomography (PET)/CT scan and curative surgery between January 2012 and August 2014. The total abdominal muscle area (TAMA), subcutaneous fat area (SFA), and visceral fat area (VFA) were measured on CT images at the L3 vertebral level. Univariate and multivariate Cox proportional-hazard regression analyses were performed to evaluate whether there was an association between sarcopenia and overall survival (OS) outcome. Results: Of the 577 women, 49 (8.5%) died after a mean of 46 months. The best TAMA threshold for predicting OS was 83.7 cm2 . The multivariate Cox proportional-hazard analysis revealed that sarcopenia (TAMA ≤ 83.70 cm2 ) was a strong prognostic biomarker (hazard ratio [HR], 1.951; 95% confidence interval [CI], 1.061–3.586), along with large tumor size, axillary lymph node metastasis, high nuclear grade, estrogen receptor status, and adjuvant radiation therapy. In the subgroup analysis of patients aged ≥ 50 years, TAMA (≤ 77.14 cm2 ) was a significant independent factor (HR, 2.856; 95% CI, 1.218–6.695). Conclusion: Skeletal muscle depletion measured on CT was associated with worse OS outcome in patients with non-metastatic breast cancer
목차
등록된 정보가 없습니다.
참고문헌 (29)
참고문헌 신청
Siegel RL / 2018 / Cancer statistics, 2018 / CA Cancer J Clin 68:7~30
Early Breast Cancer Trialists' Collaborative Group(EBCTCG) / 2012 / Comparisons between different polychemotherapy regimens for early breast cancer: meta-analyses of long-term outcome among 100,000 women in 123 randomised trials / Lancet 379:432~444
Early Breast Cancer Trialists' Collaborative Group(EBCTCG) / 2011 / Relevance of breast cancer hormone receptors and other factors to the efficacy of adjuvant tamoxifen : patient-level meta-analysis of randomised trials / Lancet 378:771~784
O'Sullivan CC / 2015 / Efficacy of Adjuvant trastuzumab for patients with human epidermal growth factor receptor 2-positive early breast cancer and tumors ≤ 2 cm : a meta-analysis of the randomized trastuzumab trials / J Clin Oncol 33:2600~2608
DeSantis C / 2014 / Breast cancer statistics, 2013 / CA Cancer J Clin 64:52~62
Early Breast Cancer Trialists' Collaborative Group(EBCTCG) / 2012 / Comparisons between different polychemotherapy regimens for early breast cancer: meta-analyses of long-term outcome among 100,000 women in 123 randomised trials / Lancet 379:432~444
Early Breast Cancer Trialists' Collaborative Group(EBCTCG) / 2011 / Relevance of breast cancer hormone receptors and other factors to the efficacy of adjuvant tamoxifen : patient-level meta-analysis of randomised trials / Lancet 378:771~784
O'Sullivan CC / 2015 / Efficacy of Adjuvant trastuzumab for patients with human epidermal growth factor receptor 2-positive early breast cancer and tumors ≤ 2 cm : a meta-analysis of the randomized trastuzumab trials / J Clin Oncol 33:2600~2608
DeSantis C / 2014 / Breast cancer statistics, 2013 / CA Cancer J Clin 64:52~62
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Lymph Node Ratio as a Good Prognostic Factor for Patients with Pathologic N3a Breast Cancer with 10 or More Metastatic Axillary Lymph Nodes
Journal of Breast Disease
2021 .12
-
Prognostic Effect of Breast Cancer Subtypes in Metastatic Breast Cancer Patients
대한임상종양학회 학술대회지
2015 .02
-
The prognosis factors among breast cancer patients with extensive axillary lymph node metastasis
KOREAN JOURNAL OF CLINICAL ONCOLOGY
2018 .06
-
A comparative study of the clinical characteristics of breast cancer patients less than 35 years old and older patients
KOREAN JOURNAL OF CLINICAL ONCOLOGY
2018 .06
-
Lymph node ratio as a prognostic factor for pathologic N3a breast cancer patients with 10 or more metastatic axillary lymph nodes
대한외과학회 학술대회 초록집
2017 .11
-
Prognostic Value of Lymph Node Ratio in Pathologic N3a Breast Cancer Patients with Ten or More Metastatic Axillary Lymph Nodes
대한외과학회 학술대회 초록집
2021 .11
-
Prognostic Factors for Risk Stratification of Patients with Recurrent or Metastatic Pancreatic Adenocarcinoma Who Were Treated with Gemcitabine-Based Chemotherapy
Cancer Research and Treatment
2016 .01
-
Clinicopathologic Features and Long-Term Outcomes of Elderly Breast Cancer Patients: Experiences at a Single Institution in Korea
Cancer Research and Treatment
2016 .01
-
호르몬 수용체 약양성 유방암과 삼중음성 유방암의 치료 예후
Journal of Breast Disease
2019 .01
-
Operable Breast Cancer of the Inner Hemisphere Is Associated with Poor Survival
Journal of Breast Cancer
2015 .01
-
Chronological Improvement in Survival of Patients with Breast Cancer: A Large-Scale, Single-Center Study
Journal of Breast Cancer
2018 .01
-
Breast Cancer Metastatic to Gluteus Maximus: A Case Report
Journal of Breast Disease
2023 .06
-
Prognostic Factors for Survival in Patients with Breast Cancer Referred to Omitted Cancer Research Center in Iran
Asian Pacific journal of cancer prevention : APJCP
2015 .01
-
Effect of Hormone Therapy on Long-term Outcomes of Patients with Human Epidermal Growth Factor Receptor 2-and Hormone Receptor-Positive Metastatic Breast Cancer: Real World Experience in China
Asian Pacific journal of cancer prevention : APJCP
2015 .01
-
Impact on Survival of Regular Postoperative Surveillance for Patients with Early Breast Cancer
Cancer Research and Treatment
2015 .01
-
Omission of Chemotherapy for the Treatment of Mucinous Breast Cancer: A Nationwide Study from the Korean Breast Cancer Society
Journal of Breast Cancer
2019 .01
-
A comparative study of the clinical characteristics and outcomes of HR-positive HER2-negative breast cancer patients over and under 65 years old
KOREAN JOURNAL OF CLINICAL ONCOLOGY
2021 .06
-
Effects of Less than 60 Days Delay in Surgery on Tumor Progression and Survival Outcomes in Invasive Breast Cancer Patients
Journal of Breast Disease
2016 .12
-
Immunohistochemistry Biomarkers Predict Survival in Stage II/III Gastric Cancer Patients: From a Prospective Clinical Trial
Cancer Research and Treatment
2019 .01
-
Quantitative Measurement of Serum MicroRNA-21 Expression in Relation to Breast Cancer Metastasis in Chinese Females
Annals of Laboratory Medicine
2015 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0