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논문 기본 정보

자료유형
학술저널
저자정보
Kim Si-Ho (Center for Infection Prevention and Control Samsung Changwon Hospital Changwon Korea.) Wi Yu Mi (Division of Infectious Diseases Samsung Changwon Hospital Sungkyunkwan University Changwon Korea.) Yun Su Yeon (Center for Infection Prevention and Control Samsung Changwon Hospital Changwon Korea.) Ryu Jeong Seon (Center for Infection Prevention and Control Samsung Changwon Hospital Changwon Korea.) Shin Jung Min (Center for Infection Prevention and Control Samsung Changwon Hospital Changwon Korea.) Lee Eun Hui (Center for Infection Prevention and Control Samsung Changwon Hospital Changwon Korea.) Seo Kyung Hwa (Center for Infection Prevention and Control Samsung Changwon Hospital Changwon Korea.) Lee Sung Hee (Center for Infection Prevention and Control Samsung Changwon Hospital Changwon Korea.) Peck Kyong Ran (Division of Infectious Diseases Samsung Medical Center Sungkyunkwan University School of Medicine S)
저널정보
대한의학회 Journal of Korean Medical Science Journal of Korean Medical Science Vol.36 No.14
발행연도
2021.1
수록면
1 - 8 (8page)

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초록· 키워드

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Coronavirus disease 2019 vaccinations for healthcare workers (HCWs) have begun in South Korea. To investigate adverse events (AEs) of the first dose of each vaccine, any symptom was collected daily for seven days after vaccination in a tertiary hospital. We found that 1,301 of 1,403 ChAdOx1 nCoV-19 recipients and 38 of 80 BNT162b2 recipients reported AEs respectively (90.9% vs. 52.5%): injection-site pain (77.7% vs. 51.2%), myalgia (60.5% vs. 11.2%), fatigue (50.7% vs. 7.5%), headache (47.4% vs. 7.5%), and fever (36.1% vs. 5%; P < 0.001 for all). Young HCWs reported more AEs with ChAdOx1 nCoV-19 than with BNT162b2. No incidences of anaphylaxis were observed. Only one serious AE required hospitalization for serious vomiting, and completely recovered. In conclusion, reported AEs were more common in recipients with ChAdOx1 nCoV-19 than in those with BNT162b2. However, most of the reported AEs were mild to moderate in severity. Sufficient explanation and preparation for expected AEs required to promote widespread vaccination.

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