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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한백신학회 Clinical and Experimental Vaccine Research Clinical and Experimental Vaccine Research Vol.10 No.3
- 발행연도
- 2021.9
- 수록면
- 282 - 294 (13page)
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초록· 키워드
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Purpose: This study was conducted to determine differences in adverse events associated with the first and second doses of the BNT162b2 coronavirus disease 2019 vaccine based on the age and sex of recipients.
Materials and Methods: An online survey on the post-vaccination adverse events of healthcare workers was conducted from March 2021 to April 2021. The differences in the types of adverse events, including severity, onset time, and duration of symptoms, and how the adverse events were dealt with by the patient were analyzed based on the age and sex. The profiles of adverse events were compared after the first and second vaccination doses.
Results: Among the 131 participants who participated in the online survey out of 208 vaccine recipients, 43 and 80 recipients of the BNT162b2 vaccine experienced adverse events after the first and second dose, respectively. No sex-related differences were observed in the profiles of adverse events in vaccinated recipients. The overall frequency of adverse events did not differ based on age after the first dose. After the second dose, the frequency of adverse events, including both local and systemic reactions was significantly higher in the younger age group than in the older age group.
Conclusion: The BNT162b2 vaccine resulted in a higher frequency of adverse events after the second dose than after the first dose especially in the younger age group; however, no sex-related differences associated with these adverse events were observed.
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참고문헌 (17)
참고문헌 신청
Korea Disease Control and Prevention Agency / Current COVID-19 vaccination status in Korea
Polack FP / 2020 / Safety and efficacy of the BNT162b2 mRNA COVID-19 vaccine / N Engl J Med 383:2603~2615
Zimmermann P / 2019 / Factors that influence the immune response to vaccination / Clin Microbiol Rev 32:e00084~e00018
Kurupati R / 2016 / Race-related differences in antibody responses to the inactivated influenza vaccine are linked to distinct pre-vaccination gene expression profiles in blood / Oncotarget 7:62898~62911
Haralambieva IH / 2014 / Associations between race, sex and immune response variations to rubella vaccination in two independent cohorts / Vaccine 32:1946~1953
Polack FP / 2020 / Safety and efficacy of the BNT162b2 mRNA COVID-19 vaccine / N Engl J Med 383:2603~2615
Zimmermann P / 2019 / Factors that influence the immune response to vaccination / Clin Microbiol Rev 32:e00084~e00018
Kurupati R / 2016 / Race-related differences in antibody responses to the inactivated influenza vaccine are linked to distinct pre-vaccination gene expression profiles in blood / Oncotarget 7:62898~62911
Haralambieva IH / 2014 / Associations between race, sex and immune response variations to rubella vaccination in two independent cohorts / Vaccine 32:1946~1953
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