지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2020.1
- 수록면
- 960 - 964 (5page)
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초록· 키워드
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Appropriate reference intervals of serum insulin-like growth factor I (IGF-I) is important for diagnosing and monitoring patients with growth hormone-related diseases. To establish reference intervals, adult individuals (n=1,334, 680 men and 654 women) were divided into six age groups (20–29, 30–39, 40–49, 50–59, 60–69, ≥70). Serum IGF-I was measured by chemiluminescence immunoassay (Liaison). Concordance of patient classification based on reference intervals, manufacturer’s intervals, and standard deviation score (SDS) was evaluated. New reference intervals had higher upper and lower limits than those specified by the manufacturer. The agreement between classification using new reference interval and the manufacturer’s reference interval, and that using new reference interval and SDS was 75.0% (weighted kappa, 0.17), 91.9% (weighted kappa, 0.51) in men and 91.0% (weighted kappa, 0.41), 92.5% (weighted kappa, 0.53) in women, respectively. Reference intervals should be established not only based on age and sex, but also on ethnicity and assay method.
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등록된 정보가 없습니다.
참고문헌 (15)
참고문헌 신청
Mavromati M / 2017 / Classification of patients with GH disorders may vary according to the IGF-I assay / J Clin Endocrinol Metab 102:2844~2852
Dogansen SC / 2018 / Impact of glucose metabolism disorders on IGF-1 levels in patients with acromegaly / Horm Metab Res 50:408~413
Hyun SE / 2012 / Reference values for serum levels of insulin-like growth factor-I and insulin-like growth factor binding protein-3 in Korean children and adolescents / Clin Biochem 45:16~21
최현국 / 2009 / 건강한 성인에서 인슐린양 성장 인자-1의 농도 및 관련 요인 / Korean Journal of Family Medicine 30(1):15~22
Zhu H / 2017 / Reference ranges for serum insulin-like growth factor I(IGF-I)in healthy Chinese adults / PLoS One 12:e0185561
Dogansen SC / 2018 / Impact of glucose metabolism disorders on IGF-1 levels in patients with acromegaly / Horm Metab Res 50:408~413
Hyun SE / 2012 / Reference values for serum levels of insulin-like growth factor-I and insulin-like growth factor binding protein-3 in Korean children and adolescents / Clin Biochem 45:16~21
최현국 / 2009 / 건강한 성인에서 인슐린양 성장 인자-1의 농도 및 관련 요인 / Korean Journal of Family Medicine 30(1):15~22
Zhu H / 2017 / Reference ranges for serum insulin-like growth factor I(IGF-I)in healthy Chinese adults / PLoS One 12:e0185561
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