지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2020.1
- 수록면
- 85 - 95 (11page)
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초록· 키워드
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Background/Aims: Patients with inflammatory bowel disease (IBD) are usually hospitalized because of aggravated gastrointestinal symptoms. Many clinicians empirically advise these patients to fast once they are admitted. However, there has been no evidence that maintaining a complete bowel rest improves the disease course. Therefore, we aimed to investigate the effects of fasting on disease course in admitted patients with IBD or intestinal Behçet’s disease. Methods: A total of 222 patients with IBD or intestinal Behçet’s disease, who were admitted for disease-related symptoms, were retrospectively analyzed. We divided them into 2 groups: fasting group (allowed to take sips of water but no food at the time of admission) and dietary group (received liquid, soft, or general diet). Results: On admission, 124 patients (55.9%) started fasting and 98 patients (44.1%) started diet immediately. Among patients hospitalized through the emergency room, a significantly higher proportion underwent fasting (63.7% vs. 21.4%, P<0.001); however, 96.0% of the patients experienced dietary changes. Corticosteroid use (P<0.001; hazard ratio, 2.445; 95% confidence interval, 1.506–3.969) was significantly associated with a reduction in the disease activity score, although there was no significant difference between the fasting group and the dietary group in disease activity reduction (P=0.111) on multivariate analysis. Conclusions: In terms of disease activity reduction, there was no significant difference between the fasting and dietary groups in admitted patients with IBD, suggesting that imprudent fasting is not helpful in improving the disease course. Therefore, peroral diet should not be avoided unless not tolerated by the patient.
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참고문헌 (48)
참고문헌 신청
Thia KT / 2008 / An update on the epidemiology of inflammatory bowel disease in Asia / Am J Gastroenterol 103:3167~3182
Broström O / 1990 / Prognosis in ulcerative colitis / Med Clin North Am 74:201~218
Solberg IC / 2009 / Clinical course during the first 10 years of ulcerative colitis : results from a population-based inception cohort(IBSEN Study) / Scand J Gastroenterol 44:431~440
Tadakazu Hisamatsu / 2017 / Treatment and outcomes: medical and surgical treatment for intestinal Behçet’s disease / Intestinal research 15(3):318~327
Yong Eun Park / 2018 / Updated treatment strategies for intestinal Behçet’s disease / The Korean Journal of Internal Medicine 33(1):1~19
Broström O / 1990 / Prognosis in ulcerative colitis / Med Clin North Am 74:201~218
Solberg IC / 2009 / Clinical course during the first 10 years of ulcerative colitis : results from a population-based inception cohort(IBSEN Study) / Scand J Gastroenterol 44:431~440
Tadakazu Hisamatsu / 2017 / Treatment and outcomes: medical and surgical treatment for intestinal Behçet’s disease / Intestinal research 15(3):318~327
Yong Eun Park / 2018 / Updated treatment strategies for intestinal Behçet’s disease / The Korean Journal of Internal Medicine 33(1):1~19
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