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학술저널
저자정보
Ajit Sood (Dayanand Medical College) Kirandeep Kaur (Dayanand Medical College) Ramit Mahajan (Dayanand Medical College & Hospital) Vandana Midha (Dayanand Medical College) Arshdeep Singh (Dayanand Medical College & Hospital) Sarit Sharma (Dayanand Medical College and Hospital) Amarender Singh Puri (Department of Gastroenterology GB Pant Hospital New Delhi India) Bhabhadev Goswami (Gauhati Medical College Guwahati) Devendra Desai (P. D. Hinduja Hospital and Medical Research Centre Mumbai) C. Ganesh Pai (Kasturba Medical College) Kiran Peddi (Citizens Centre for Digestive Disorders Hyderabad) Mathew Philip (Lisie Institute of Gastroenterology) Rakesh Kochhar (Postgraduate Institute of Medical Education and Research) Sandeep Nijhawan (Department of Gastroenterology Sawai Man Singh Medical College) Shobna Bhatia (King Edward Memorial Hospital Mumbai) N. Sridhara Rao (Purnachandra Gastroenterology Institute)
저널정보
대한장연구학회 Intestinal research Intestinal research Vol.19 No.2
발행연도
2021.1
수록면
206 - 216 (11page)

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Background/Aims: The national registry for inflammatory bowel disease (IBD) was designed to study epidemiology and prescribing pattern of treatment of IBD in India. Methods: A multicenter, cross-sectional, prospective registry was established across four geographical zones of India. Adult patients with ulcerative colitis (UC) or Crohn’s disease (CD) were enrolled between January 2014 and December 2015. Information related to demographics; disease features; complications; and treat- ment history were collected and analyzed. Results: A total of 3,863 patients (mean age, 36.7 ± 13.6 years; 3,232 UC [83.7%] and 631 CD [16.3%]) were enrolled. The majority of patients with UC (n = 1,870, 57.9%) were from north, CD was more common in south (n = 348, 55.5%). The UC:CD ratio was 5.1:1. There was a male predominance (male:female = 1.6:1). The commonest presentation of UC was moderately severe (n = 1,939, 60%) and E2 disease (n = 1,895, 58.6%). Patients with CD most commonly presented with ileocolonic (n = 229, 36.3%) inflammatory (n = 504, 79.9%) disease. Extraintestinal manifestations were recorded among 13% and 20% of patients in UC and CD respectively. Less than 1% patients from both cohorts developed colon cancer (n = 26, 0.7%). The commonly used drugs were 5-aminosalicylates (99%) in both UC and CD followed by azathioprine (34.4%). Biologics were used in only 1.5% of patients; more commonly for UC in north and CD in south. Conclusions: The national IBD registry brings out diversities in the 4 geographical zones of India. This will help in aiding research on IBD and improving qual- ity of patient care.

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