지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2024.8
- 수록면
- 131 - 150 (20page)
이용수
초록· 키워드
오류제보하기
Objectives : The aim of this study was to perform network analysis and analysis using the K-HERB database on inflammatory bowel disease (IBD), to verify the similarity between the derived networks and existing prescriptions, and to explore the possibility of developing new IBD prescriptions preliminarily.
Methods : We conducted a comprehensive literature search on July 6, 2024, utilizing databases such as ScienceON, RISS, and OASIS. Clinical studies assessing the efficacy of herbal medicine in treating Crohn’s disease and ulcerative colitis were identified and compiled into a structured database. This dataset, which included related prescriptions and herbal formulations, was subsequently analyzed using NetMiner 4 for centrality and Louvain clustering analyses. We then compared the networks derived from the K-HERB database with existing therapeutic prescriptions to assess their similarity.
Results : A total of 24 prescriptions and 66 herbs were identified across the surveyed studies on IBD. Paeoniae Radix Alba(白芍藥) emerged as the most frequently utilized herb for both Crohn’s disease and ulcerative colitis. Prominent herb combinations included Paeoniae Radix Alba-Angelicae Sinensis Radix (白芍藥-當歸), Angelicae Sinensis Radix-Coptidis Rhizoma (當歸-黃連), and Coptidis Rhizoma-Scutellariae Radix (黃連-黃芩) for ulcerative colitis. Centrality analysis revealed that Poria cocos (茯苓) and Paeoniae Radix Alba (白芍藥) had high centrality in the Crohn’s disease, while Angelicae Sinensis Radix (當歸) and Paeoniae Radix Alba (白芍藥) had high centrality in the ulcerative colitis, indicating their prominent roles within the networks. Cohesion analysis resulted in 7 networks for Crohn's disease and 16 networks for ulcerative colitis. After excluding networks with a single herb, three networks related to Crohn’s disease and two related to ulcerative colitis were examined using the K-HERB database. Among the 14 derived prescriptions for Crohn’s disease and seven for ulcerative colitis, all except Oryeong-san (五苓散) were non-traditional in the context of IBD treatment.
Conclusion : This preliminary study may provide a basis for the understanding and application of herbal prescriptions for IBD based on network analysis and the K-HERB database.
목차
등록된 정보가 없습니다.
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
염증성 장질환의 약물요법
대한의사협회지
2015 .01
-
Factors related to Quality of Life of Patients with Ulcerative Colitis
성인간호학회 학술대회
2015 .04
-
Is the Long-term Disease Course of Elderly-Onset Ulcerative Colitis Different from That of Non-Elderly-Onset Ulcerative Colitis?
Gut and Liver
2021 .09
-
Ulcerative Colitis and Patient’s Quality of Life, Especially in Early Stage
Gut and Liver
2022 .05
-
Best practices on immunomodulators and biologic agents for ulcerative colitis and Crohn’s disease in Asia
Intestinal research
2019 .01
-
Mitochondrial dysfunction of epithelial cell drives submucosal thickening through inflammatory fibroblasts in ulcerative colitis
한국실험동물학회 학술발표대회 논문집
2025 .02
-
Landscape of inflammatory bowel disease in Singapore
Intestinal research
2022 .07
-
청소년궤양성 대장염 환자의 사상체질요법에 대한 증례보고
대한한방내과학회지
2017 .01
-
Precision medicine in inflammatory bowel diseases
Intestinal research
2024 .01
-
Disability due to Inflammatory Bowel Disease Is Correlated with Drug Compliance, Disease Activity, and Quality of Life
Gut and Liver
2017 .01
-
Artificial intelligence for endoscopy in inflammatory bowel disease
Intestinal research
2022 .04
-
Colitis and Crohn’s Foundation (India): a first nationwide inflammatory bowel disease registry
Intestinal research
2021 .01
-
Navigating the Microbial Basis of Inflammatory Bowel Diseases: Seeing the Light at the End of the Tunnel
Gut and Liver
2016 .01
-
Current and Emerging Biologics for Ulcerative Colitis
Gut and Liver
2015 .01
-
Association of Vitamin D with Inflammatory Bowel Disease Activity in Pediatric Patients
Journal of Korean Medical Science
2019 .01
-
Incidence and Prevalence of Inflammatory Bowel Disease across Asia
Yonsei Medical Journal
2021 .01
-
Sarcopenia is common in ulcerative colitis and correlates with disease activity
Intestinal research
2024 .04
-
The impact of clinical experience on decision-making regarding the treatment and management of mild-to-moderate ulcerative colitis
Intestinal research
2023 .01
-
Pathogenesis of Inflammatory Bowel Disease and Recent Advances in Biologic Therapies
Immune Network
2017 .02
-
염증장질환의 치료: 생물학적제제 및 새로운 치료법을 중심으로
대한의사협회지
2021 .09
최근 본 자료
댓글(0)
0