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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.1
- 수록면
- 1 - 12 (12page)
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Background: To evaluate oral anticoagulant (OAC) utilization in patients with atrial fibrillation after the changes in the health insurance coverage policy in July 2015. Methods: We used the Health Insurance Review and Assessment Service-National Patient Samples (HIRA-NPS) between 2014 and 2016. The HIRA-NPS, including approximately 1.4 million individuals, is a stratified random sample of 3% of the entire Korean population using 16 age groups and 2 sex groups. The HIRA-NPS comprises personal and medical information such as surgical or medical treatment provided, diagnoses, age, sex, region of medical institution, and clinician characteristics. The studied drugs included non-vitamin K antagonist OACs (NOACs) such as apixaban, dabigatran, edoxaban, and rivaroxaban, and were compared with warfarin. We analyzed drug utilization pattern under three aspects: person, time, and place. Results: The number of patients with atrial fibrillation who were prescribed OACs was 3,114, 3,954, and 4,828; and the proportions of prescribed NOACs to total OACs were 5.1%, 36.2%, and 60.8% in 2014, 2015, and 2016, respectively. The growth rate of OACs prescription increased from 61.4 patients/quarter before June 2015 to 147.7 patients/quarter thereafter. These changes were predominantly in elderly individuals aged more than 70 years. The proportion of NOACs to OACs showed significant regional difference. Conclusion: The change of health insurance coverage policy substantially influenced OACs prescription pattern in whole Korean region. But the impact has been significantly different among regions and age groups, which provides the evidence for developing standard clinical practice guideline on OACs use.
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참고문헌 (22)
참고문헌 신청
Go AS / 2001 / Prevalence of diagnosed atrial fibrillation in adults: national implications for rhythm management and stroke prevention: the AnTicoagulation and Risk Factors in Atrial Fibrillation (ATRIA) Study / JAMA 285(18):2370~2375
Wolf PA / 1991 / Atrial fibrillation as an independent risk factor for stroke: the Framingham Study / Stroke 22(8):983~988
Wilke T / 2013 / Incidence and prevalence of atrial fibrillation: an analysis based on 8.3 million patients / Europace 15(4):486~493
Rahman F / 2014 / Global epidemiology of atrial fibrillation / Nat Rev Cardiol 11(11):639~654
Lee SR / 2017 / Trends in the incidence and prevalence of atrial fibrillation and estimated thromboembolic risk using the CHA2DS2-VASc score in the entire Korean population / Int J Cardiol 236:226~231
Wolf PA / 1991 / Atrial fibrillation as an independent risk factor for stroke: the Framingham Study / Stroke 22(8):983~988
Wilke T / 2013 / Incidence and prevalence of atrial fibrillation: an analysis based on 8.3 million patients / Europace 15(4):486~493
Rahman F / 2014 / Global epidemiology of atrial fibrillation / Nat Rev Cardiol 11(11):639~654
Lee SR / 2017 / Trends in the incidence and prevalence of atrial fibrillation and estimated thromboembolic risk using the CHA2DS2-VASc score in the entire Korean population / Int J Cardiol 236:226~231
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