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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.1
- 수록면
- 220 - 227 (8page)
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Despite the rapid development of therapeutic modalities for metastatic renal cell carcinoma (mRCC) over the past decade to include a number of targeted antiangiogenic therapies and traditional immunotherapy, such as high-dose interleukin-2 and interferon-α, mRCC continues to be associated with poor prognosis. Currently, several novel immunotherapy agents, such as cancer vaccines, adoptive cell therapy, and checkpoint inhibitors, such as programmed cell death-1 (PD-1 present on T cells), one of its ligands (PD-L1 present on antigen-presenting cells and tumor cells), and cytotoxic T-lymphocyte-associated protein-4 pathways, are being studied in mRCC and are showing promise as important steps in the management of this disease. This review summarizes the current landscape of standard and emerging immune therapeutics and other modalities for mRCC.
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참고문헌 (62)
참고문헌 신청
Canadian Cancer Society’s Advisory Committee on Cancer Statistics / 2015 / Canadian cancer statistics 2015 / Canadian Cancer Society
Ljungberg B / 2011 / Corrigendum to "The epidemiology of renal cell carcinoma" [Eur Urol 2011;60:615-21] / Eur Urol 60:1317
Athar U / 2008 / Treatment options for metastatic renal cell carcinoma: a review / Can J Urol 15:3954~3966
Gupta K / 2008 / Epidemiologic and socioeconomic burden of metastatic renal cell carcinoma (mRCC): a literature review / Cancer Treat Rev 34:193~205
Rosenberg SA / 1987 / A progress report on the treatment of 157 patients with advanced cancer using lymphokine-activated killer cells and interleukin-2 or high-dose interleukin-2 alone / N Engl J Med 316:889~897
Ljungberg B / 2011 / Corrigendum to "The epidemiology of renal cell carcinoma" [Eur Urol 2011;60:615-21] / Eur Urol 60:1317
Athar U / 2008 / Treatment options for metastatic renal cell carcinoma: a review / Can J Urol 15:3954~3966
Gupta K / 2008 / Epidemiologic and socioeconomic burden of metastatic renal cell carcinoma (mRCC): a literature review / Cancer Treat Rev 34:193~205
Rosenberg SA / 1987 / A progress report on the treatment of 157 patients with advanced cancer using lymphokine-activated killer cells and interleukin-2 or high-dose interleukin-2 alone / N Engl J Med 316:889~897
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