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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.1
- 수록면
- 4 - 16 (13page)
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초록· 키워드
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Because anti-tumor necrosis factor (anti-TNF) therapy has become increasingly popular in many Asian countries, the risk of developing active tuberculosis (TB) among anti-TNF users may raise serious health problems in this region. Thus, the AsianOrganization for Crohn’s and Colitis and the Asia Pacific Association of Gastroenterology have developed a set of consensus statements about risk assessment, detection and prevention of latent TB infection, and management of active TB infection inpatients with inflammatory bowel disease (IBD) receiving anti-TNF treatment. Twenty-three consensus statements were initially drafted and then discussed by the committee members. The quality of evidence and the strength of recommendations were assessed by using the Grading of Recommendations Assessment, Development, and Evaluation methodology. Web-based consensus voting was performed by 211 IBD specialists from 9 Asian countries concerning each statement. A consensusstatement was accepted if at least 75% of the participants agreed. Part 1 of the statements comprised 2 parts: risk of TB infection during anti-TNF therapy, and screening for TB infection prior to commencing anti-TNF therapy. These consensus statementswill help clinicians optimize patient outcomes by reducing the morbidity and mortality related to TB infections in patients withIBD receiving anti-TNF treatment.
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참고문헌 (90)
참고문헌 신청
Getahun H / 2015 / Latent Mycobacterium tuberculosis infection / N Engl J Med 372:2127~2135
Mack U / 2009 / LTBI: latent tuberculosis infection or lasting immune responses to M. tuberculosis? A TBNET consensus statement / Eur Respir J 33:956~973
Fallahi-Sichani M / 2011 / Multiscale computational modeling reveals a critical role for TNF-alpha receptor 1 dynamics in tuberculosis granuloma formation / J Immunol 186:3472~3483
Roach DR / 2002 / TNF regulates chemokine induction essential for cell recruitment, granuloma formation, and clearance of mycobacterial infection / J Immunol 168:4620~4627
Mohan VP / 2001 / Effects of tumor necrosis factor alpha on host immune response in chronic persistent tuberculosis: possible role for limiting pathology / Infect Immun 69:1847~1855
Mack U / 2009 / LTBI: latent tuberculosis infection or lasting immune responses to M. tuberculosis? A TBNET consensus statement / Eur Respir J 33:956~973
Fallahi-Sichani M / 2011 / Multiscale computational modeling reveals a critical role for TNF-alpha receptor 1 dynamics in tuberculosis granuloma formation / J Immunol 186:3472~3483
Roach DR / 2002 / TNF regulates chemokine induction essential for cell recruitment, granuloma formation, and clearance of mycobacterial infection / J Immunol 168:4620~4627
Mohan VP / 2001 / Effects of tumor necrosis factor alpha on host immune response in chronic persistent tuberculosis: possible role for limiting pathology / Infect Immun 69:1847~1855
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