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논문 기본 정보

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저자정보
Dong Il Park (Kangbuk Samsung Hospital Sungkyunkwan University School of Medicine) Tadakazu Hisamatsu (Keio University School of Medicine) Min-Hu Chen (Sun Yat-Sen University) Siew Chien Ng (The Chinese University of Hong Kong) Choon Jin Ooi (Gleneagles Medical Centre and Duke-NUS Medical School) Shu Chen Wei (National Taiwan University College of Medicine) Rupa Banerjee (Asian Institute of Gastroenterology Hyderabad India) Ida Normiha Hilmi (Department of Medicine University of Malaya) Yoon Tae Jeen (Korea University College of Medicine) 한동수 (한양대학교) Hyo Jong Kim (Kyung Hee University School of Medicine) Zhi Hua Ran (Shanghai Jiao Tong University China) Kaichun Wu (Fourth Military Medical University) Jiaming Qian (Peking Union Medical College) Pin-Jin Hu (Sun Yat-sen University) Katsuyoshi Matsuoka (Department of Gastroenterology and Hepatology Tokyo Medical and Dental University Tokyo Japan) Akira Andoh (Shiga University) Yasuo Suzuki (Department of Internal Medicine Toho University Sakura Medical Center) Kentaro Sugano (Jichi Medical University) Mamoru Watanabe (Department of Gastroenterology and Hepatology Tokyo Medical and Dental University Tokyo Japan) Toshifumi Hibi (Kitasato University) Amarender S. Puri (Govind Ballabh Pant Institute of Postgraduate Medical Education and Research) 양석균 (울산대학교)
저널정보
대한장연구학회 Intestinal research Intestinal research Vol.16 No.1
발행연도
2018.1
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17 - 25 (9page)

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Because anti-tumor necrosis factor (anti-TNF) therapy has become increasingly popular in many Asian countries, the risk of developing active tuberculosis (TB) among anti-TNF users may raise serious health problems in this region. Thus, the Asian Organization for Crohn’s and Colitis and the Asia Pacific Association of Gastroenterology have developed a set of consensus statements about risk assessment, detection and prevention of latent TB infection, and management of active TB infection in patients with inflammatory bowel disease (IBD) receiving anti-TNF treatment. Twenty-three consensus statements were initially drafted and then discussed by the committee members. The quality of evidence and the strength of recommendations were assessed by using the Grading of Recommendations Assessment, Development, and Evaluation methodology. Web- based consensus voting was performed by 211 IBD specialists from 9 Asian countries concerning each statement. A consensus statement was accepted if at least 75% of the participants agreed. Part 2 of the statements comprised 3 parts: management of latent TB in preparation for anti-TNF therapy, monitoring during anti-TNF therapy, and management of an active TB infection after anti-TNF therapy. These consensus statements will help clinicians optimize patient outcomes by reducing the morbidity and mortality related to TB infections in patients with IBD receiving anti-TNF treatment.

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참고문헌 (65)

참고문헌 신청
Keane J / 2001 / Tuberculosis associated with infliximab, a tumor necrosis factor alpha-neutralizing agent / N Engl J Med 345:1098~1104 Crossref Gomez-Reino JJ / 2003 / Treatment of rheumatoid arthritis with tumor necrosis factor inhibitors may predispose to significant increase in tuberculosis risk: a multicenter active- surveillance report / Arthritis Rheum 48:2122~2127 Crossref Souto A / 2014 / Risk of tuberculosis in patients with chronic immune-mediated inflammatory diseases treated with biologics and tofacitinib: a systematic review and meta-analysis of randomized controlled trials and long-term extension studies / Rheumatology (Oxford) 53:1872~1885 Crossref Cantini F / 2014 / Adalimumab, etanercept, infliximab, and the risk of tuberculosis: data from clinical trials, national registries, and postmarketing surveillance / J Rheumatol Suppl 91:47~55 Crossref Lorenzetti R / 2014 / Higher risk of tuberculosis reactivation when anti-TNF is combined with immunosuppressive agents: a systematic review of randomized controlled trials / Ann Med 46:547~554 Crossref

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