지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
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In addition to cognitive and functional decline, various behavioral and psychological symptoms in dementia (BPSD) are manifested in the patients with Alzheimer’s dementia (AD). Some of BPSD, especially psychosis, agitation, and aggression could be challenges to caregivers and clinicians. Atypical antipsychotic drugs (risperidone, olanzapine, quetiapine, and aripiprazole) are widely prescribed to manage complicated neuropsychiatric symptoms associated with AD. It is known that atypical antipsychotics (AAP) have modest and significant beneficial effects in the short term treatment of BPSD. However their safety of AAP has been concerned with potentially increased adverse events. This article reviewed the treatment outcomes and adverse effects of AAP when managing BPSD in the patients with AD. The effects of risperidone and aripiprazole are obvious on psychosis and aggression, but with small effect size. AAP could exacerbate
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등록된 정보가 없습니다.
참고문헌 (50)
참고문헌 신청
Jost BC / 1996 / The evolution of psychiatric symptoms in Alzheimer’s disease : a natural history study / J Am Geriatr Soc 44:1078~1081
Steinberg M / 2008 / Point and 5-year period prevalence of neuropsychiatric symptoms in dementia : the Cache County Study / Int J Geriatr Psychiatry 23:170~177
Benoit M / 2003 / Behavioral and psychologic symptoms in Alzheimer’s disease: results of the REAL.FR study / Rev Med Interne 24(Suppl 3):319s~324s
Chan DC / 2003 / Presence of behavioral and psychological symptoms predicts nursing home placement in community-dwelling elders with cognitive impairment in univariate but not multivariate analysis / J Gerontol A Biol Sci Med Sci 58:548~554
Aalten P / 2003 / Behavioral problems in dementia : a factor analysis of the neuropsychiatric inventory / Dement Geriatr Cogn Disord 15:99~105
Steinberg M / 2008 / Point and 5-year period prevalence of neuropsychiatric symptoms in dementia : the Cache County Study / Int J Geriatr Psychiatry 23:170~177
Benoit M / 2003 / Behavioral and psychologic symptoms in Alzheimer’s disease: results of the REAL.FR study / Rev Med Interne 24(Suppl 3):319s~324s
Chan DC / 2003 / Presence of behavioral and psychological symptoms predicts nursing home placement in community-dwelling elders with cognitive impairment in univariate but not multivariate analysis / J Gerontol A Biol Sci Med Sci 58:548~554
Aalten P / 2003 / Behavioral problems in dementia : a factor analysis of the neuropsychiatric inventory / Dement Geriatr Cogn Disord 15:99~105
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