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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2021.10
- 수록면
- 526 - 536 (11page)
- DOI
- https://doi.org/10.9799/ksfan.2021.34.5.526
이용수
초록· 키워드
오류제보하기
This study was conducted to investigate the anti-obesity effect of Discorea Japonica Thunb. fermented with Monascus After inducing obesity by feeding hight fat diet (diet induced obesity model: DIO) for four weeks, each 8 rats were assigned to normal (Nor), high fat diet (HF), high fat diet containing orlistat (PC), high fat diet containing different concentration of Discorea Japonica Thunb. fermented with Monascus (UPDM_L, UPDM_H) and Discorea Japonica Thunb. (UPD) extract. Although the UPD, UPDM_L (ultrafine pulverized Discorea Japonica Thunb. fermented with Monascus: 400 mg/kg) and UPDM_H (DIO oral administration ultrafine pulverized Discorea Japonica Thunb. fermented with Monascus: 800 mg/kg) showed weight gain inhibition effects, the results of poor obesity inhibition rather than PC were confirmed. However, it showed a more effective weight loss effect in UPDM_H than UPD, and significantly reduced the weight of epididymal fat and subcutaneous fat. Furthermore, the possibility of anti-obesity effects of Discorea Japonica Thunb. fermented with Monascus can be confirmed by observing the effects of reducing serum total cholesterol, triglyceride and LDL concentrations, reducing ALT and AST levels, and inhibiting fat build-up in liver tissue. It is believed that Discorea Japonica Thunb. fermented with Monascus can be expected to utilize as a functional material that is important to improve anti-obesity and metabolic syndrome.
목차
등록된 정보가 없습니다.
참고문헌 (41)
참고문헌 신청
Cardel MI / 2020 / Obesity treatment among adolescents : A review of current evidence and future directions / JAMA Pediatr 174:609~617
Cardiff RD / 2014 / Manual hematoxylin and eosin staining of mouse tissue sections / Cold Spring Harb Protoc 2014:655~658
차재영 / 2009 / 홍국발효홍삼 분말 급여에 의한 흰쥐의 혈청 지질 농도 및 항산화 활성에 미치는 영향 / 한국식품영양과학회지 38(9):1153~1160
Chen HL / 2003 / Effects of Taiwanese yam(Dioscorea japonica Thunb var. pseudojaponica Yamamoto)on upper gut function and lipid metabolism in Balb/c mice / Nutrition 19:646~651
Choi HW / 2018 / Anti-inflammatory effect of lovastatin is mediated via the modulation of NF-κB and inhibition of HDAC1 and the PI3K/Akt/mTOR pathway in RAW264. 7 macrophages / Int J Mol Med 41:1103~1109
Cardiff RD / 2014 / Manual hematoxylin and eosin staining of mouse tissue sections / Cold Spring Harb Protoc 2014:655~658
차재영 / 2009 / 홍국발효홍삼 분말 급여에 의한 흰쥐의 혈청 지질 농도 및 항산화 활성에 미치는 영향 / 한국식품영양과학회지 38(9):1153~1160
Chen HL / 2003 / Effects of Taiwanese yam(Dioscorea japonica Thunb var. pseudojaponica Yamamoto)on upper gut function and lipid metabolism in Balb/c mice / Nutrition 19:646~651
Choi HW / 2018 / Anti-inflammatory effect of lovastatin is mediated via the modulation of NF-κB and inhibition of HDAC1 and the PI3K/Akt/mTOR pathway in RAW264. 7 macrophages / Int J Mol Med 41:1103~1109
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