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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.8
- 수록면
- 77 - 81 (5page)
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Purpose: To assess the antibiotic susceptibility of Escherichia coli from commu-nity-acquired uncomplicated urinary tract infection (UTI).Materials and Methods: Between August and December of 2015, confirmed cases of E. coli as a pathogen of community-acquired uncomplicated UTI were collected and assessed for antibiotic susceptibility in 10 designated hospitals. Additional fosfomycin susceptibility test was performed by a central laboratory using the disk diffusion method.Results: A total of 347 E. coli isolates were collected from urine samples of community-acquired uncomplicated UTIs patients. The susceptibility rates of antibiotics were as follows: amikacin 100.0% (347), imipenem 100.0% (347), ciprofloxacin 57.1% (198), cefotaxime 74.9% (260), ampicillin 30.0% (104), trimethoprim/sulfamethoxazole 66.9% (232), and fosfomycin 98.0% (340). All fosfomycin-resistant E. coli isolates were extended-spectrum ?-lactamase (ESBL)-producing. In 85 cases of ESBL-producing E. coli, the fosfomycin susceptibility rate was 91.8% (78/85).Conclusions: Fosfomycin may be a useful option for the treatment of community-acquired uncomplicated UTIs. Further studies evaluating the role of fosfomycin in the treatment of UTIs and its clinical efficacy are necessary.
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참고문헌 (19)
참고문헌 신청
Hooton TM / 2012 / Clinical practice. Uncomplicated urinary tract infection / N Engl J Med 366:1028~1037
Jorgensen JH / 2009 / Antimicrobial susceptibility testing: a review of general principles and contemporary practices / Clin Infect Dis 49:1749~1755
Kim HY / 2016 / Microbiological characteristics of unresolved acute uncomplicated cystitis / Microb Drug Resist 22:387~391
Miller LG / 2004 / Treatment of uncomplicated urinary tract infections in an era of increasing antimicrobial resistance / Mayo Clin Proc 79:1048~1053
Dhariwal AK / 2013 / Colistin: re-emergence of the ‘forgotten' antimicrobial agent / J Postgrad Med 59:208~215
Jorgensen JH / 2009 / Antimicrobial susceptibility testing: a review of general principles and contemporary practices / Clin Infect Dis 49:1749~1755
Kim HY / 2016 / Microbiological characteristics of unresolved acute uncomplicated cystitis / Microb Drug Resist 22:387~391
Miller LG / 2004 / Treatment of uncomplicated urinary tract infections in an era of increasing antimicrobial resistance / Mayo Clin Proc 79:1048~1053
Dhariwal AK / 2013 / Colistin: re-emergence of the ‘forgotten' antimicrobial agent / J Postgrad Med 59:208~215
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