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논문 기본 정보

자료유형
학술저널
저자정보
Elaheh Asgari (Department of Community Nutrition School of Nutritional Sciences and Dietetics Tehran University of Medical Sciences (TUMS) Tehran 14155-6117 Iran.) Farideh Shiraseb (Department of Community Nutrition School of Nutritional Sciences and Dietetics Tehran University of Medical Sciences (TUMS) Tehran 14155-6117 Iran.) Atieh Mirzababaei (Department of Community Nutrition School of Nutritional Sciences and Dietetics Tehran University of Medical Sciences (TUMS) Tehran 14155-6117 Iran.) Hadith Tangestani (Department of Nutrition Persian Gulf Tropical Medicine Research Center Bushehr University of Medical Sciences Bushehr 7518759577 Iran.) Khadijeh Mirzaei (Department of Community Nutrition School of Nutritional Sciences and Dietetics Tehran University of Medical Sciences (TUMS) Tehran 14155-6117 Iran.)
저널정보
한국임상영양학회 Clinical Nutrition Research Clinical Nutrition Research Vol.12 No.1
발행연도
2023.1
수록면
7 - 20 (14page)
DOI
10.7762/cnr.2023.12.1.7

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Creating a complex balance between dietary composition, circadian rhythm, and the hemostasis control of energy is important for managing diseases. Therefore, we aimed to determine the interaction between cryptochrome circadian clocks 1 polymorphism and energy-adjusted dietary inflammatory index (E-DII) on high-sensitivity C-reactive protein in women with central obesity. This cross-sectional study recruited 220 Iranian women aged 18–45 with central obesity. The 147-item semi-quantitative food frequency questionnaire was used to assess the dietary intakes, and the E-DII score was calculated. Anthropometric and biochemical measurements were determined. By polymerase chain response-restricted length polymorphism method, cryptochrome circadian clocks 1 polymorphism was assigned. Participants were categorized into three groups based on the E-DII score, then categorized according to cryptochrome circadian clocks 1 genotypes. The mean and standard deviation of age, BMI, and high-sensitivity C-reactive protein (hs-CRP) were 35.61 ± 9.57 years, 30.97 ± 4.16 kg/m2 , and 4.82 ± 5.16 mg/dL, respectively. The interaction of the CG genotype and E-DII score had a significant association with higher hs-CRP level compared to GG genotype as the reference group (β, 1.19; 95% CI, 0.11–2.27; p value, 0.03). There was a marginally significant association between the interaction of the CC genotype and the E-DII score with higher hs-CRP level compared to the GG genotype as the reference group (β, 0.85; 95% CI, −0.15 to 1.86; p value, 0.05). There is probably positive interaction between CG, CC genotypes of cryptochrome circadian clocks 1, and E-DII score on the high-sensitivity C-reactive protein level in women with central obesity.

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