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논문 기본 정보

자료유형
학술저널
저자정보
고한이 (한국교원대학교) 김경래 (한국교원대학교) 서태범 (제주대학교)
저널정보
한국교원대학교 뇌기반교육연구소 Brain, Digital, & Learning Brain, Digital, & Learning 제14권 제3호
발행연도
2024.9
수록면
431 - 444 (14page)

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초록· 키워드

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This study investigates the combined effects of protein intake and swimming exercise on theexpression of key growth factors (BDNF, IGF-1, VEGF) and stress-related hormones (CRHBP,cortisol, epinephrine). Six-week-old ICR male mice were divided into four groups based ondietary and exercise interventions: Group 1 received a protein diet with exercise (PEG), Group2 received a protein diet without exercise (PNEG), Group 3 was provided with a proteinfreediet with exercise (NPEG) and Group 4 was given a protein-free diet without exercise(NPNEG). After a 6-week experimental period, BDNF, IGF-1, and VEGF mRNA expressionlevels were analyzed using the Real-Time Loop-Mediated Isothermal Amplification (RT-LAMP)method. In contrast, the levels of stress-related hormones were measured through ELISA. The results reveal significant impacts of dietary protein intake and swimming exercise on theexpression of these critical markers. BDNF and IGF-1 levels were highest in PEG, highlightingthe beneficial effects of combining protein intake with swimming exercise. VEGF expressionalso showed significant differences, particularly between PNEG and NPNEG, and PNEG andPEG. CRHBP, cortisol, and epinephrine levels varied significantly across groups, especiallybetween those subjected to different dietary and exercise regimens. This suggests a stronginteraction between protein intake and exercise in modulating stress responses. In conclusion, the study demonstrates that protein intake and swimming exercisesynergistically influence the expression of growth factors and stress hormones in mice. These findings provide valuable insights into the physiological adaptations to diet andexercise in mammals, which could inform future research on optimizing dietary and exerciseinterventions for health and stress management.

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