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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.1
- 수록면
- 975 - 980 (6page)
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Since its introduction as an alternative intestinal microbiota alteration approach, fecal microbiota transplantation (FMT) has been increasingly used as a treatment of choice for patients with ulcerative colitis (UC), but no reports exist regarding FMT via percutaneous endoscopic cecostomy (PEC). This report describes the case of a 24-year-old man with a 7-year history of recurrent, steroid-dependent UC. He received FMT via PEC once per day for 1 month in the hospital. After the remission of gastrointestinal symptoms, he was discharged from the hospital and continued FMT via PEC twice per week for 3 months at home. The frequency of stools decreased, and the characteristics of stools improved soon thereafter.
Enteral nutrition was regained after 1 week, and an oral diet was begun 1 month later. Two months after the FMT end point, the patient resumed a normal diet, with formed soft stools once per day. The follow-up colonoscopy showed normal mucus membranes; then, the PEC set was removed. On the subsequent 12 months follow-up, the patient resumed orthobiosis without any gastrointestinal discomfort and returned to work. This case emphasizes that FMT via PEC can not only induce remission but also shorten the duration of hospitalization and reduce the medical costs; therefore, this approach should be considered an alternative option for patients with UC.
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참고문헌 (26)
참고문헌 신청
Kane SV / 2006 / Systematic review: adherence issues in the treatment of ulcerative colitis / Aliment Pharmacol Ther 23:577~585
Tinsley A / 2015 / Early readmission in patients hospitalized for ulcerative colitis:incidence and risk factors / Scand J Gastroenterol 50:1103~1109
Anderson JL / 2012 / Systematic review: faecal microbiota transplantation in the management of inflammatory bowel disease / Aliment Pharmacol Ther 36:503~516
Talley NJ / 2011 / An evidence-based systematic review on medical therapies for inflammatory bowel disease / Am J Gastroenterol 106(1):S2~S25
박성철 / 2015 / Current and Emerging Biologics for Ulcerative Colitis / Gut and Liver 9(1):18~27
Tinsley A / 2015 / Early readmission in patients hospitalized for ulcerative colitis:incidence and risk factors / Scand J Gastroenterol 50:1103~1109
Anderson JL / 2012 / Systematic review: faecal microbiota transplantation in the management of inflammatory bowel disease / Aliment Pharmacol Ther 36:503~516
Talley NJ / 2011 / An evidence-based systematic review on medical therapies for inflammatory bowel disease / Am J Gastroenterol 106(1):S2~S25
박성철 / 2015 / Current and Emerging Biologics for Ulcerative Colitis / Gut and Liver 9(1):18~27
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